rs12623467
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common in complete genomics |
| Make rs12623467(C;T) |
| Make rs12623467(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 2 |
| Position | 50997951 |
| Gene | NRXN1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs12623467 |
| dbSNP (classic) | rs12623467 |
| ClinGen | rs12623467 |
| ebi | rs12623467 |
| HLI | rs12623467 |
| Exac | rs12623467 |
| Gnomad | rs12623467 |
| Varsome | rs12623467 |
| LitVar | rs12623467 |
| Map | rs12623467 |
| PheGenI | rs12623467 |
| Biobank | rs12623467 |
| 1000 genomes | rs12623467 |
| hgdp | rs12623467 |
| ensembl | rs12623467 |
| geneview | rs12623467 |
| scholar | rs12623467 |
| rs12623467 | |
| pharmgkb | rs12623467 |
| gwascentral | rs12623467 |
| openSNP | rs12623467 |
| 23andMe | rs12623467 |
| SNPshot | rs12623467 |
| SNPdbe | rs12623467 |
| MSV3d | rs12623467 |
| GWAS Ctlg | rs12623467 |
| GMAF | 0.2103 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs12623467 increases susceptibility to Substance dependence, Nicotine 2.09 times for carriers of the C allele [PMID 17158188
]
[PMID 18270208] Significant association of the neurexin-1 gene (NRXN1) with nicotine dependence in European- and African-American smokers.
[PMID 18565990] Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence.
[PMID 18783506] Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking.
