| Geno
|
Mag
|
Summary
|
| (T;T)
|
0
|
common on affy axiom data
|
| GWAS snp
|
| PMID
|
[PMID 21102463 ]
|
| Trait
|
|
| Title
|
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
|
| Risk Allele
|
G
|
| P-val
|
1E-12
|
| Odds Ratio
|
1.1200 [1.06-1.19]
|
| GWAS snp
|
| PMID
|
[PMID 20953190]
|
| Trait
|
|
| Title
|
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
|
| Risk Allele
|
A
|
| P-val
|
4E-11
|
| Odds Ratio
|
1.4000 [1.23-1.61]
|
[PMID 21140222] Meta-analysis of TYK2 gene polymorphisms association with susceptibility to autoimmune and inflammatory diseases
[PMID 15657875] Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus.
[PMID 18270328] Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia.
[PMID 19249008] Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease.
[PMID 19434718] Variants in interferon-alpha pathway genes and response to pegylated interferon-Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long-term treatment against cirrhosis trial.
[PMID 19604093] Genetic polymorphisms, their allele combinations and IFN-beta treatment response in Irish multiple sclerosis patients.
[PMID 19653082] Strong evidence of a combination polymorphism of the tyrosine kinase 2 gene and the signal transducer and activator of transcription 3 gene as a DNA-based biomarker for susceptibility to Crohn's disease in the Japanese population.
[PMID 23000200] TYK2 rs34536443 polymorphism is associated with a decreased susceptibility to endometriosis-related infertility.
[PMID 26338038] Influence of TYK2 in systemic sclerosis susceptibility: a new locus in the IL-12 pathway
]
