| GWAS
|
| SNP
|
rs13015714
|
| PubMedID
|
[PMID 18311140 ]
|
| Condition
|
Celiac disease
|
| Gene
|
IL1RL1,IL18R1,IL18RAP, SLC9A4
|
| Risk Allele
|
C
|
| pValue
|
4.00E-009
|
| OR
|
1.28
|
| 95% CI
|
1.18-1.39
|
| OMIM | 612006 |
| Desc | CELIAC DISEASE, SUSCEPTIBILITY TO, 8; CELIAC8 |
| Variant | |
| Related | also |
[PMID 19693089] Four novel coeliac disease regions replicated in an association study of a Swedish-Norwegian family cohort
[PMID 18853133
] Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.
[PMID 19103669] Association study of the IL18RAP locus in three European populations with coeliac disease.
[PMID 19468064
] Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions.
| GWAS snp
|
| PMID
|
[PMID 23042114]
|
| Trait
|
Atopic dermatitis
|
| Title
|
Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population.
|
| Risk Allele
|
G
|
| P-val
|
8E-18
|
| Odds Ratio
|
1.27 [1.20-1.34]
|
[PMID 26399911
] Associations between interleukin and interleukin receptor gene polymorphisms and risk of gout
[PMID 32185238
] Haplotype Analysis of Candidate Genes Involved in Inflammation and Oxidative Stress and the Susceptibility to Preeclampsia.