rs13119723
| Orientation | plus |
| Stabilized | plus |
| Make rs13119723(A;A) |
| Make rs13119723(A;G) |
| Make rs13119723(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 4 |
| Position | 122297158 |
| Gene | KIAA1109 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs13119723 |
| dbSNP (classic) | rs13119723 |
| ClinGen | rs13119723 |
| ebi | rs13119723 |
| HLI | rs13119723 |
| Exac | rs13119723 |
| Gnomad | rs13119723 |
| Varsome | rs13119723 |
| LitVar | rs13119723 |
| Map | rs13119723 |
| PheGenI | rs13119723 |
| Biobank | rs13119723 |
| 1000 genomes | rs13119723 |
| hgdp | rs13119723 |
| ensembl | rs13119723 |
| geneview | rs13119723 |
| scholar | rs13119723 |
| rs13119723 | |
| pharmgkb | rs13119723 |
| gwascentral | rs13119723 |
| openSNP | rs13119723 |
| 23andMe | rs13119723 |
| SNPshot | rs13119723 |
| SNPdbe | rs13119723 |
| MSV3d | rs13119723 |
| GWAS Ctlg | rs13119723 |
| GMAF | 0.06841 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
Of SNPs outside the HLA region, this SNP and one other (rs6822844) in the region of the IL21 gene showed the strongest association with celiac disease in a study of ~800 Caucasian patients and a meta-analysis of two further populations.[PMID 17558408
]
[PMID 19455118] Novel Genetic Risk Markers for Ulcerative Colitis in the IL2/IL21 Region Are in Epistasis With IL23R and Suggest a Common Genetic Background for Ulcerative Colitis and Celiac Disease
[PMID 19201773] Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis
[PMID 20184734] The 4q27 locus and familial prostate cancer risk
| GWAS snp | |
|---|---|
| PMID | [PMID 20453842]
|
| Trait | Rheumatoid arthritis |
| Title | Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk lock |
| Risk Allele | A |
| P-val | 7E-7 |
| Odds Ratio | 1.12 [NR] |
[PMID 22355377] Caucasian and asian specific rheumatoid arthritis risk Loci reveal limited replication and apparent allelic heterogeneity in north indians
[PMID 18311140] Newly identified genetic risk variants for celiac disease related to the immune response.
[PMID 18369459] A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.
[PMID 18418394] Association study of IL2/IL21 and FcgRIIa: significant association with the IL2/IL21 region in Scandinavian coeliac disease families.
[PMID 19061490] FitSNPs: highly differentially expressed genes are more likely to have variants associated with disease.
[PMID 19176549] Genome-wide association analysis by lasso penalized logistic regression.
[PMID 20553587] Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.
[PMID 21304239] Analysis of IL2/IL21 gene variants in cholestatic liver diseases reveals an association with primary sclerosing cholangitis.
