rs13208776
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | normal | |
| (A;G) | normal | |
| (G;G) | higher risk for generalized vitiligo |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 168540944 |
| Gene | SMOC2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs13208776 |
| dbSNP (classic) | rs13208776 |
| ClinGen | rs13208776 |
| ebi | rs13208776 |
| HLI | rs13208776 |
| Exac | rs13208776 |
| Gnomad | rs13208776 |
| Varsome | rs13208776 |
| LitVar | rs13208776 |
| Map | rs13208776 |
| PheGenI | rs13208776 |
| Biobank | rs13208776 |
| 1000 genomes | rs13208776 |
| hgdp | rs13208776 |
| ensembl | rs13208776 |
| geneview | rs13208776 |
| scholar | rs13208776 |
| rs13208776 | |
| pharmgkb | rs13208776 |
| gwascentral | rs13208776 |
| openSNP | rs13208776 |
| 23andMe | rs13208776 |
| SNPshot | rs13208776 |
| SNPdbe | rs13208776 |
| MSV3d | rs13208776 |
| GWAS Ctlg | rs13208776 |
| GMAF | 0.1561 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs13208776 is a SNP in the SPARC related modular calcium binding 2 SMOC2 gene.
A genome-wide association study (GWAS) of generalized vitiligo in 32 distantly related affected patients from a remote Romanian village identified rs13208776 as highly associated with the disorder, at an odds ratio of 7.445 (CI: 3.5-15.3, p=8x10e-8) and a population attributable risk of 28.[PMID 19890347
]
[PMID 20965805] SMOC2 gene variant and the risk of vitiligo in Jordanian Arabs
[PMID 23463390] Variants in PTPN22 and SMOC2 genes and the risk of thyroid disease in the Jordanian Arab population.
