rs13208776
From SNPedia
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(A;A) | normal | |
(A;G) | normal | |
(G;G) | higher risk for generalized vitiligo |
Reference | GRCh38 38.1/141 |
Chromosome | 6 |
Position | 168540944 |
Gene | SMOC2 |
is a | snp |
is | mentioned by |
dbSNP | rs13208776 |
dbSNP (classic) | rs13208776 |
ClinGen | rs13208776 |
ebi | rs13208776 |
HLI | rs13208776 |
Exac | rs13208776 |
Gnomad | rs13208776 |
Varsome | rs13208776 |
LitVar | rs13208776 |
Map | rs13208776 |
PheGenI | rs13208776 |
Biobank | rs13208776 |
1000 genomes | rs13208776 |
hgdp | rs13208776 |
ensembl | rs13208776 |
geneview | rs13208776 |
scholar | rs13208776 |
rs13208776 | |
pharmgkb | rs13208776 |
gwascentral | rs13208776 |
openSNP | rs13208776 |
23andMe | rs13208776 |
SNPshot | rs13208776 |
SNPdbe | rs13208776 |
MSV3d | rs13208776 |
GWAS Ctlg | rs13208776 |
GMAF | 0.1561 |
Max Magnitude | 0 |
? | (A;A) (A;G) (G;G) | 28 |
---|---|---|
|
rs13208776 is a SNP in the SPARC related modular calcium binding 2 SMOC2 gene.
A genome-wide association study (GWAS) of generalized vitiligo in 32 distantly related affected patients from a remote Romanian village identified rs13208776 as highly associated with the disorder, at an odds ratio of 7.445 (CI: 3.5-15.3, p=8x10e-8) and a population attributable risk of 28.[PMID 19890347]
[PMID 20965805] SMOC2 gene variant and the risk of vitiligo in Jordanian Arabs
[PMID 23463390] Variants in PTPN22 and SMOC2 genes and the risk of thyroid disease in the Jordanian Arab population.