|(A;A)||1.25||1.24x increased risk for breast cancer|
|(A;G)||1.1||1.12x increased risk for breast cancer|
This initial association was later tested among patients in the Breast Cancer Association Consortium, including 31,510 women with invasive breast cancer, 1101 women with ductal carcinoma in situ (DCIS), and 35,969 controls. In Caucasian women of European origin, each A allele is associated with 1.12 higher odds (CI: 1.09-1.15). This association held regardless of ER or PR status. [PMID 19567422]
|Title||A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1)|
[PMID 19789366] Evaluation of 11 breast cancer susceptibility loci in African-American women
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|Odds Ratio||1.21 [1.14-1.29]|
[PMID 20664043] Incidence of breast cancer and its subtypes in relation to individual and multiple low-penetrance genetic susceptibility loci
|Title||A combined analysis of genome-wide association studies in breast cancer|
|Odds Ratio||1.18 [1.10-1.27]|
|Title||Novel Breast Cancer Susceptibility Locus at 9q31.2: Results of a Genome-Wide Association Study|
|Odds Ratio||1.1600 [1.11-1.22]|
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|Odds Ratio||1.14 [1.11-1.16]|
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