rs144567652
From SNPedia
| rare variant associated with breast cancer risk |
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common/normal |
| (C;T) | 3 | ~3x higher breast cancer risk |
| Make rs144567652(T;T) |
| Reference | GRCh38.p2 38.2/144 |
| Chromosome | 14 |
| Position | 45198718 |
| Gene | FANCM |
| is a | snp |
| is | mentioned by |
| dbSNP | rs144567652 |
| dbSNP (classic) | rs144567652 |
| ClinGen | rs144567652 |
| ebi | rs144567652 |
| HLI | rs144567652 |
| Exac | rs144567652 |
| Gnomad | rs144567652 |
| Varsome | rs144567652 |
| LitVar | rs144567652 |
| Map | rs144567652 |
| PheGenI | rs144567652 |
| Biobank | rs144567652 |
| 1000 genomes | rs144567652 |
| hgdp | rs144567652 |
| ensembl | rs144567652 |
| geneview | rs144567652 |
| scholar | rs144567652 |
| rs144567652 | |
| pharmgkb | rs144567652 |
| gwascentral | rs144567652 |
| openSNP | rs144567652 |
| 23andMe | rs144567652 |
| SNPshot | rs144567652 |
| SNPdbe | rs144567652 |
| MSV3d | rs144567652 |
| GWAS Ctlg | rs144567652 |
| Max Magnitude | 3 |
rs144567652, also known as c.5791C>T, p.Arg1931Ter and R1931X, is a SNP in the FANCM gene.
Genotyping 8,635 familial breast cancer cases led to an association with rs144567652, (odds ratio 3.93, CI:1.28-12.11, p=0.017), and two subsequent meta-analyses showed similar [breast cancer]] associations (odds ratio 3.67, CI:1.04-12.87, p=0.043, and, OR of 3.33, CI:1.09-13.62, p=0.032), respectively.[PMID 26130695
]
Note: a name used by 23andMe for this SNP is i6050899.
