rs1678542
| Orientation | minus |
| Stabilized | minus |
| Make rs1678542(C;C) |
| Make rs1678542(C;G) |
| Make rs1678542(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 12 |
| Position | 57574932 |
| Gene | KIF5A |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1678542 |
| dbSNP (classic) | rs1678542 |
| ClinGen | rs1678542 |
| ebi | rs1678542 |
| HLI | rs1678542 |
| Exac | rs1678542 |
| Gnomad | rs1678542 |
| Varsome | rs1678542 |
| LitVar | rs1678542 |
| Map | rs1678542 |
| PheGenI | rs1678542 |
| Biobank | rs1678542 |
| 1000 genomes | rs1678542 |
| hgdp | rs1678542 |
| ensembl | rs1678542 |
| geneview | rs1678542 |
| scholar | rs1678542 |
| rs1678542 | |
| pharmgkb | rs1678542 |
| gwascentral | rs1678542 |
| openSNP | rs1678542 |
| 23andMe | rs1678542 |
| SNPshot | rs1678542 |
| SNPdbe | rs1678542 |
| MSV3d | rs1678542 |
| GWAS Ctlg | rs1678542 |
| GMAF | 0.4793 |
| Max Magnitude | 0 |
| ? | (C;C) (C;G) (G;G) | 28 |
|---|---|---|
|
| ||
| GWAS | |
|---|---|
| SNP | rs1678542 |
| PubMedID | [PMID 18794853 ]
|
| Condition | Rheumatoid arthritis |
| Gene | KIF5A-PIP4K2C |
| Risk Allele | C |
| pValue | 9.00E-008 |
| OR | 1.12 |
| 95% CI | |
[PMID 19956108] Analysis of 55 autoimmune disease and type II diabetes loci: further confirmation of chromosomes 4q27, 12q13.2 and 12q24.13 as type I diabetes loci, and support for a new locus, 12q13.3-q14.1
[PMID 20508602] The autoimmune disease-associated KIF5A, CD226 and SH2B3 gene variants confer susceptibility for multiple sclerosis
[PMID 20498205] Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers
[PMID 19674979] Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis.
[PMID 20439292] Genetic variants in the prediction of rheumatoid arthritis.
[PMID 20444755] Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment.
[PMID 23378462] Replication of European Rheumatoid Arthritis Loci in a Pakistani Population
[PMID 22328738] Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.
| GWAS snp | |
|---|---|
| PMID | [PMID 24449572]
|
| Trait | Rheumatoid arthritis |
| Title | Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study. |
| Risk Allele | |
| P-val | 1E-7 |
| Odds Ratio | 1.20 [1.12-1.28] |
[PMID 26092158] IRF5, PTPN22, CD28, IL2RA, KIF5A, BLK and TNFAIP3 genes polymorphisms and lupus susceptibility in a cohort from the Egypt Delta; relation to other ethnic groups
