rs17036314
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | risk of progressing from IGT to T2D; reduced by exercise | |
| (C;G) | risk of progressing from IGT to T2D; reduced by exercise | |
| (G;G) | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 3 |
| Position | 12335246 |
| Gene | PPARG |
| is a | snp |
| is | mentioned by |
| dbSNP | rs17036314 |
| dbSNP (classic) | rs17036314 |
| ClinGen | rs17036314 |
| ebi | rs17036314 |
| HLI | rs17036314 |
| Exac | rs17036314 |
| Gnomad | rs17036314 |
| Varsome | rs17036314 |
| LitVar | rs17036314 |
| Map | rs17036314 |
| PheGenI | rs17036314 |
| Biobank | rs17036314 |
| 1000 genomes | rs17036314 |
| hgdp | rs17036314 |
| ensembl | rs17036314 |
| geneview | rs17036314 |
| scholar | rs17036314 |
| rs17036314 | |
| pharmgkb | rs17036314 |
| gwascentral | rs17036314 |
| openSNP | rs17036314 |
| 23andMe | rs17036314 |
| SNPshot | rs17036314 |
| SNPdbe | rs17036314 |
| MSV3d | rs17036314 |
| GWAS Ctlg | rs17036314 |
| GMAF | 0.2681 |
| Max Magnitude | 0 |
| ? | (C;C) (C;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs17036314 is a SNP in the peroxisome proliferator-activated receptor gamma PPARG gene.
In a 4 year study of 479 overweight individuals with impaired glucose tolerance (IGT) who participated in the Finnish Diabetes Prevention Study (DPS), carrying a rs17036314(C) allele predicted conversion to type-2 diabetes (T2D) after adjustment for baseline fasting glucose (p=0.030). Increased physical activity reduced this risk.[PMID 18091023]
