rs17222842

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(G;G)	0	common in complete genomics

Make rs17222842(A;A)

Make rs17222842(A;G)

Reference

GRCh38 38.1/141

Chromosome

13

Position

30765980

Gene

ALOX5AP

is a	snp
is	mentioned by
dbSNP	rs17222842
dbSNP (classic)	rs17222842
ClinGen	rs17222842
ebi	rs17222842
HLI	rs17222842
Exac	rs17222842
Gnomad	rs17222842
Varsome	rs17222842
LitVar	rs17222842
Map	rs17222842
PheGenI	rs17222842
Biobank	rs17222842
1000 genomes	rs17222842
hgdp	rs17222842
ensembl	rs17222842
geneview	rs17222842
scholar	rs17222842
google	rs17222842
pharmgkb	rs17222842
gwascentral	rs17222842
openSNP	rs17222842
23andMe	rs17222842
SNPshot	rs17222842
SNPdbe	rs17222842
MSV3d	rs17222842
GWAS Ctlg	rs17222842

GMAF

0.03857

Max Magnitude

0

rs17222842, also known as SG13S35, is an ALOX5AP gene SNP that has been defined as part of a haplotype potentially associated with risk for myocardial infarction or ischemic stroke. Details of this haplotype and several related studies are on the ALOX5AP page.

[PMID 19130089] Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis.

[PMID 19361804] 5-Lipoxygenase activating protein (ALOX5AP) gene variants associate with the presence of xanthomas in familial hypercholesterolemia.

[PMID 19751821] Oxidative risk for atherothrombotic cardiovascular disease.

[PMID 27893808] Common Polymorphisms in the 5-Lipoxygenase Pathway and Risk of Incident Myocardial Infarction: A Danish Case-Cohort Study.