rs17238484
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Make rs17238484(G;G) |
| Make rs17238484(G;T) |
| Make rs17238484(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 5 |
| Position | 75352671 |
| Gene | HMGCR |
| is a | snp |
| is | mentioned by |
| dbSNP | rs17238484 |
| dbSNP (classic) | rs17238484 |
| ClinGen | rs17238484 |
| ebi | rs17238484 |
| HLI | rs17238484 |
| Exac | rs17238484 |
| Gnomad | rs17238484 |
| Varsome | rs17238484 |
| LitVar | rs17238484 |
| Map | rs17238484 |
| PheGenI | rs17238484 |
| Biobank | rs17238484 |
| 1000 genomes | rs17238484 |
| hgdp | rs17238484 |
| ensembl | rs17238484 |
| geneview | rs17238484 |
| scholar | rs17238484 |
| rs17238484 | |
| pharmgkb | rs17238484 |
| gwascentral | rs17238484 |
| openSNP | rs17238484 |
| 23andMe | rs17238484 |
| SNPshot | rs17238484 |
| SNPdbe | rs17238484 |
| MSV3d | rs17238484 |
| GWAS Ctlg | rs17238484 |
| Max Magnitude | 0 |
http://www.medscape.com/viewarticle/832327
Each additional allele of rs17238484(G) was associated with a mean 0.06-mmol/L lower LDL-cholesterol level. Similar reductions were associated with rs12916 SNP. In addition, they found that each additional allele of rs17238484-G was associated with a higher body weight (0.30 kg), waist circumference (0.32 cm), and plasma insulin concentration (1.62%) and plasma glucose concentration (0.23%). Again, the rs12916 SNP had similar effect
[PMID 25262344
] HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials
