rs174550
| Orientation | plus |
| Stabilized | plus |
| Make rs174550(C;C) |
| Make rs174550(C;T) |
| Make rs174550(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 11 |
| Position | 61804006 |
| Gene | FADS1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs174550 |
| dbSNP (classic) | rs174550 |
| ClinGen | rs174550 |
| ebi | rs174550 |
| HLI | rs174550 |
| Exac | rs174550 |
| Gnomad | rs174550 |
| Varsome | rs174550 |
| LitVar | rs174550 |
| Map | rs174550 |
| PheGenI | rs174550 |
| Biobank | rs174550 |
| 1000 genomes | rs174550 |
| hgdp | rs174550 |
| ensembl | rs174550 |
| geneview | rs174550 |
| scholar | rs174550 |
| rs174550 | |
| pharmgkb | rs174550 |
| gwascentral | rs174550 |
| openSNP | rs174550 |
| 23andMe | rs174550 |
| SNPshot | rs174550 |
| SNPdbe | rs174550 |
| MSV3d | rs174550 |
| GWAS Ctlg | rs174550 |
| GMAF | 0.3297 |
| Max Magnitude | 0 |
[PMID 21421807
] In a study conducted on 6,580 Nondiabetic Finnish Men, the glucose-increasing T allele of rs174550 in FADS1 was significantly associated with high concentrations of very large and large HDL particles, particle diameter, and nominally associated with low concentrations of all VLDL particles.
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
| GWAS snp | |
|---|---|
| PMID | [PMID 20081858]
|
| Trait | Fasting glucose-related traits |
| Title | New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk |
| Risk Allele | T |
| P-val | 5E-13 |
| Odds Ratio | None None |
[PMID 21887289] Glucose-Raising Genetic Variants in MADD and ADCY5 Impair Conversion of Proinsulin to Insulin
| GWAS snp | |
|---|---|
| PMID | [PMID 21829377]
|
| Trait | |
| Title | Genetic Loci Associated with Plasma Phospholipid n-3 Fatty Acids: A Meta-Analysis of Genome-Wide Association Studies from the CHARGE Consortium. |
| Risk Allele | T |
| P-val | 1E-57 |
| Odds Ratio | 0.0800 [NR] % increase |
| GWAS snp | |
|---|---|
| PMID | [PMID 22581228]
|
| Trait | |
| Title | A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. |
| Risk Allele | |
| P-val | 2E-9 |
| Odds Ratio | None None |
[PMID 23396965] Interaction between a common variant in FADS1 and erythrocyte polyunsaturated fatty acids on lipid profile in Chinese Hans.
| GWAS snp | |
|---|---|
| PMID | [PMID 24823311]
|
| Trait | Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) |
| Title | Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium. |
| Risk Allele | T |
| P-val | 4E-140 |
| Odds Ratio | .05 [NR] unit increase |
| GWAS snp | |
|---|---|
| PMID | [PMID 24816252]
|
| Trait | Blood metabolite levels |
| Title | An atlas of genetic influences on human blood metabolites. |
| Risk Allele | T |
| P-val | 7E-24 |
| Odds Ratio | .04 [0.029-0.041] unit increase |
[PMID 28359772] GCK, GCKR, FADS1, DGKB/TMEM195 and CDKAL1 Gene Polymorphisms in Women with Gestational Diabetes.
[PMID 31991592] Genome-Wide Association Study for Serum Omega-3 and Omega-6 Polyunsaturated Fatty Acids: Exploratory Analysis of the Sex-Specific Effects and Dietary Modulation in Mediterranean Subjects with Metabolic Syndrome.
