rs17612648

plus

Geno	Mag	Summary
(C;C)	0	common in complete genomics

Make rs17612648(C;G)

Make rs17612648(G;G)

Reference

GRCh38 38.1/141

Chromosome

1

Position

198696788

Gene

PTPRC

is a	snp
is	mentioned by
dbSNP	rs17612648
dbSNP (classic)	rs17612648
ClinGen	rs17612648
ebi	rs17612648
HLI	rs17612648
Exac	rs17612648
Gnomad	rs17612648
Varsome	rs17612648
LitVar	rs17612648
Map	rs17612648
PheGenI	rs17612648
Biobank	rs17612648
1000 genomes	rs17612648
hgdp	rs17612648
ensembl	rs17612648
geneview	rs17612648
scholar	rs17612648
google	rs17612648
pharmgkb	rs17612648
gwascentral	rs17612648
openSNP	rs17612648
23andMe	rs17612648
SNPshot	rs17612648
SNPdbe	rs17612648
MSV3d	rs17612648
GWAS Ctlg	rs17612648

GMAF

0.007346

Max Magnitude

0

?

(C;C) (C;G) (G;G)

28

[PMID 19879912] No association between transmembrane protein-tyrosine-phosphatase receptor type C (CD45) exon A 77C>G transversion and Hashimoto's thyroiditis in a German population

[PMID 21067564 ] The CD45 77C/G allele is not associated with myasthenia gravis - a reassessment of the potential role of CD45 in autoimmunity

[PMID 16400609 ] Single-nucleotide polymorphisms in NAGNAG acceptors are highly predictive for variations of alternative splicing.

[PMID 18634151] No association between systemic sclerosis and C77G polymorphism in the human PTPRC (CD45) gene.

[PMID 20158892 ] Genomic features defining exonic variants that modulate splicing.

[PMID 22524693] No association between transmembrane protein-tyrosine phosphatase receptor type C (PTPRC) exon A 77C>G transversion and liver transplant rejection.

ClinVar
Risk	rs17612648(G;G) rs17612648(T;T)
Alt	rs17612648(G;G) rs17612648(T;T)
Reference	Rs17612648(C;C)
Significance	Non-pathogenic
Disease	not specified
Variation	info
Gene	PTPRC
CLNDBN	not specified
Reversed	0
HGVS	NC_000001.10:g.198665917C>G
CLNSRC
CLNACC	RCV000429422.1,

[PMID 28759630 ] C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease.