rs17810546

plus

Geno	Mag	Summary
(A;A)	0	common in complete genomics

Make rs17810546(A;G)

Make rs17810546(G;G)

Reference

GRCh38 38.1/141

Chromosome

3

Position

159947262

Gene

IL12A-AS1

is a	snp
is	mentioned by
dbSNP	rs17810546
dbSNP (classic)	rs17810546
ClinGen	rs17810546
ebi	rs17810546
HLI	rs17810546
Exac	rs17810546
Gnomad	rs17810546
Varsome	rs17810546
LitVar	rs17810546
Map	rs17810546
PheGenI	rs17810546
Biobank	rs17810546
1000 genomes	rs17810546
hgdp	rs17810546
ensembl	rs17810546
geneview	rs17810546
scholar	rs17810546
google	rs17810546
pharmgkb	rs17810546
gwascentral	rs17810546
openSNP	rs17810546
23andMe	rs17810546
SNPshot	rs17810546
SNPdbe	rs17810546
MSV3d	rs17810546
GWAS Ctlg	rs17810546

GMAF

0.05096

Max Magnitude

0

?

(A;A) (A;G) (G;G)

28

GWAS
SNP	rs17810546
PubMedID	[PMID 18311140 ]
Condition	Celiac disease
Gene	IL12A, SCHIP1
Risk Allele	G
pValue	1.00E-009
OR	1.35
95% CI	1.23-1.49

OMIM	612008
Desc	CELIAC DISEASE, SUSCEPTIBILITY TO, 10; CELIAC10
Variant
Related	also

GWAS snp
PMID	[PMID 20190752 ]
Trait	Celiac disease
Title	Multiple common variants for celiac disease influencing immune gene expression
Risk Allele	G
P-val	4E-28
Odds Ratio	1.36 [1.29-1.44]

OMIM	212750
Desc
Variant
Related	also

[PMID 22087237 ] Improving the estimation of celiac disease sibling risk by non-HLA genes

[PMID 18713140 ] Translational mini-review series on the immunogenetics of gut disease: immunogenetics of coeliac disease.

[PMID 18853133 ] Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.

[PMID 19073967 ] Shared and distinct genetic variants in type 1 diabetes and celiac disease.

[PMID 19458352 ] Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants.

[PMID 19468064 ] Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions.

[PMID 20647273 ] Investigation of type 1 diabetes and coeliac disease susceptibility loci for association with juvenile idiopathic arthritis.

GWAS snp
PMID	[PMID 23291587 ]
Trait	Behcet's disease
Title	Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1.
Risk Allele	A
P-val	6E-7
Odds Ratio	1.55 [1.30-1.85]

[PMID 25799145 ] Genome-Wide Association Study in an Admixed Case Series Reveals IL12A as a New Candidate in Behçet Disease

[PMID 31726085] Celiac disease associated snp rs17810546 is located in a gene silencing region.