rs1781735
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Make rs1781735(A;A) |
| Make rs1781735(A;C) |
| Make rs1781735(C;C) |
| Reference | GRCh38.p2 38.2/147 |
| Chromosome | 6 |
| Position | 38704303 |
| Gene | GLO1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1781735 |
| dbSNP (classic) | rs1781735 |
| ClinGen | rs1781735 |
| ebi | rs1781735 |
| HLI | rs1781735 |
| Exac | rs1781735 |
| Gnomad | rs1781735 |
| Varsome | rs1781735 |
| LitVar | rs1781735 |
| Map | rs1781735 |
| PheGenI | rs1781735 |
| Biobank | rs1781735 |
| 1000 genomes | rs1781735 |
| hgdp | rs1781735 |
| ensembl | rs1781735 |
| geneview | rs1781735 |
| scholar | rs1781735 |
| rs1781735 | |
| pharmgkb | rs1781735 |
| gwascentral | rs1781735 |
| openSNP | rs1781735 |
| 23andMe | rs1781735 |
| SNPshot | rs1781735 |
| SNPdbe | rs1781735 |
| MSV3d | rs1781735 |
| GWAS Ctlg | rs1781735 |
| Max Magnitude | 0 |
| ? | (A;A) (A;C) (C;C) | 28 |
|---|---|---|
|
| ||
[PMID 27000251] Role of glyoxalase I gene polymorphisms in late-onset epilepsy and drug-resistant epilepsy rs1781735 is a perfect proxy for rs1049346 with the G allele of rs1781735 corresponding to the C allele of rs1049346.The CC genotype of rs1049346 protects against late-onset epilepsy and drug resistant epilepsy (combined cohort, TT+TC/CC 2.645 p=0.000, and 3.049, p=0.001, respectively).
The presence of the TAC/AAT haplotypes (rs1130534-rs4746-rs1049346) may be used as a marker of predisposition to/protection against drug resistant epilepsy (combined cohorts, p=0.010 and 0.000 respectively. ORs are not provided ).
