rs1800206
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common in complete genomics |
| (C;G) |
| Make rs1800206(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 22 |
| Position | 46218377 |
| Gene | PPARA |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1800206 |
| dbSNP (classic) | rs1800206 |
| ClinGen | rs1800206 |
| ebi | rs1800206 |
| HLI | rs1800206 |
| Exac | rs1800206 |
| Gnomad | rs1800206 |
| Varsome | rs1800206 |
| LitVar | rs1800206 |
| Map | rs1800206 |
| PheGenI | rs1800206 |
| Biobank | rs1800206 |
| 1000 genomes | rs1800206 |
| hgdp | rs1800206 |
| ensembl | rs1800206 |
| geneview | rs1800206 |
| scholar | rs1800206 |
| rs1800206 | |
| pharmgkb | rs1800206 |
| gwascentral | rs1800206 |
| openSNP | rs1800206 |
| 23andMe | rs1800206 |
| SNPshot | rs1800206 |
| SNPdbe | rs1800206 |
| MSV3d | rs1800206 |
| GWAS Ctlg | rs1800206 |
| GMAF | 0.02479 |
| Max Magnitude | 0 |
| ? | (C;C) (C;G) (G;G) | 28 |
|---|---|---|
|
| ||
| ClinVar | |
|---|---|
| Risk | rs1800206(G;G) |
| Alt | rs1800206(G;G) |
| Reference | Rs1800206(C;C) |
| Significance | Other |
| Disease | Hyperapobetalipoproteinemia |
| Variation | info |
| Gene | PPARA |
| CLNDBN | Hyperapobetalipoproteinemia, susceptibility to |
| Reversed | 0 |
| HGVS | NC_000022.10:g.46614274C>G |
| CLNSRC | OMIM Allelic Variant UniProtKB (protein) |
| CLNACC | RCV000014700.2, |
[PMID 17317762] Single nucleotide polymorphisms of the peroxisome proliferator-activated receptor-alpha gene (PPARA) influence the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial.
[PMID 17850927] The PPAR-alpha gene in Alzheimer's disease: lack of replication of earlier association.
[PMID 18304332
] No evidence for association between BMI and 10 candidate genes at ages 4, 7 and 10 in a large UK sample of twins.
[PMID 18401448] PPAR Genomics and Pharmacogenomics: Implications for Cardiovascular Disease.
[PMID 18541586] Peroxisome proliferator-activated receptor [alpha] genetic variation interacts with n-6 and long-chain n-3 fatty acid intake to affect total cholesterol and LDL-cholesterol concentrations in the Atherosclerosis Risk in Communities Study.
[PMID 18549840] Cholesterol ester transfer protein, interleukin-8, peroxisome proliferator activator receptor alpha, and Toll-like receptor 4 genetic variations and risk of incident nonfatal myocardial infarction and ischemic stroke.
[PMID 18586686] Peroxisome proliferator-activated receptor-alpha (PPARA) genetic polymorphisms and breast cancer risk: a Long Island ancillary study.
[PMID 18855529] Interaction between PPARA genotype and beta-blocker treatment influences clinical outcomes following acute coronary syndromes.
[PMID 19041386] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
[PMID 19223982] Genetic Variability of RXRB, PPARA, and PPARG in Wegener's Granulomatosis.
[PMID 20414453] PPARalpha: energy combustion, hypolipidemia, inflammation and cancer.
[PMID 20811626] Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.
[PMID 21430558] Association of the peroxisome proliferator-activated receptor alpha gene L162V polymorphism with stage C heart failure.
[PMID 21487230] Effects of peroxisome proliferator-activated receptors, dietary fat intakes and gene-diet interactions on peak particle diameters of low-density lipoproteins.
[PMID 22378291] PPARgamma2 gene Pro12Ala and PPARalpha gene Leu162Val single nucleotide polymorphisms interact with dietary intake of fat in determination of plasma lipid concentrations.
[PMID 22968028] [Association of both peroxisome proliferator-activated receptor, gene-gene interactions and the body mass index]
[PMID 23262340] Gene-gene interactions among PPARα/δ/γ polymorphisms for hypertriglyceridemia in Chinese Han population
[PMID 23545576] Association of peroxisome proliferator-activated receptor α/δ/γ with obesity, and gene-gene interaction, in the Chinese Han population
[PMID 23937834] [Effects related to gene-gene interactions of peroxisome proliferator-activated receptor on essential hypertension]
[PMID 24232815] Influence of PPARA, RXRA, NR1I2 and NR1I3 gene polymorphisms on the lipid-lowering efficacy and safety of statin therapy
[PMID 23363867] [Gene-gene interactions among the peroxisome proliferator-activated receptor polymorphisms for hypertriglyceridemia]
[PMID 22920733] Investigation of endocannabinoid system genes suggests association between peroxisome proliferator activator receptor-alpha gene (PPARA) and schizophrenia.
[PMID 25294067] [Association between polymorphisms, haplotypes of peroxisome proliferators activated receptor a gene and the level of lipoprotein (a)]
[PMID 26110145] Gene-Gene Interactions among Pparα/δ/γ Polymorphisms for Apolipoprotein (Apo) A-I/Apob Ratio in Chinese Han Population
[PMID 26268872] [Association and interaction between 10 SNP of peroxisome proliferator-activated receptor and non-HDL-C]
[PMID 24599720] Effect of obesity on the association between common variations in the PPAR gene and C-reactive protein level in Chinese Han population
[PMID 26671228] The association of peroxisome proliferator-activated receptor α with diabetic retinopathy, and additional gene-obesity interaction in Chinese type 2 diabetes mellitus patients.
[PMID 28294290] Genetic Obesity Risk and Attenuation Effect of Physical Fitness in Mexican-Mestizo Population: a Case-Control Study.
[PMID 30041843] Genetic susceptibility to pre diabetes mellitus and related association with obesity and physical fitness components in Mexican-Mestizos.
