rs180177083

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(C;C)	0	common in clinvar
(C;T)	3	increased risk of breast cancer
(T;T)	7	Fanconi anemia, complementation group N

Reference

GRCh38 38.1/141

Chromosome

16

Position

23637865

Gene

PALB2

is a	snp
is	mentioned by
dbSNP	rs180177083
dbSNP (classic)	rs180177083
ClinGen	rs180177083
ebi	rs180177083
HLI	rs180177083
Exac	rs180177083
Gnomad	rs180177083
Varsome	rs180177083
LitVar	rs180177083
Map	rs180177083
PheGenI	rs180177083
Biobank	rs180177083
1000 genomes	rs180177083
hgdp	rs180177083
ensembl	rs180177083
geneview	rs180177083
scholar	rs180177083
google	rs180177083
pharmgkb	rs180177083
gwascentral	rs180177083
openSNP	rs180177083
23andMe	rs180177083
SNPshot	rs180177083
SNPdbe	rs180177083
MSV3d	rs180177083
GWAS Ctlg	rs180177083

Max Magnitude

7

ClinVar
Risk	rs180177083(A;A) Rs180177083(T;T)
Alt	rs180177083(A;A) Rs180177083(T;T)
Reference	Rs180177083(C;C)
Significance	Other
Disease	Familial cancer of breast Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	PALB2
CLNDBN	Familial cancer of breast Hereditary cancer-predisposing syndrome not provided
Reversed	1
HGVS	NC_000016.9:g.23649186G>A
CLNSRC	PALB2 database
CLNACC	RCV000114503.6, RCV000163078.2, RCV000235795.2,

[PMID 21285249] Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer.

[PMID 21409391] BRIP1, PALB2, and RAD51C mutation analysis reveals their relative importance as genetic susceptibility factors for breast cancer.