rs180177097

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(C;C)	0	common in clinvar
(C;T)	5	PALB2-related cancer risk
(T;T)	7	Fanconi anemia, complementation group N

Reference

GRCh38 38.1/141

Chromosome

16

Position

23635519

Gene

PALB2

is a	snp
is	mentioned by
dbSNP	rs180177097
dbSNP (classic)	rs180177097
ClinGen	rs180177097
ebi	rs180177097
HLI	rs180177097
Exac	rs180177097
Gnomad	rs180177097
Varsome	rs180177097
LitVar	rs180177097
Map	rs180177097
PheGenI	rs180177097
Biobank	rs180177097
1000 genomes	rs180177097
hgdp	rs180177097
ensembl	rs180177097
geneview	rs180177097
scholar	rs180177097
google	rs180177097
pharmgkb	rs180177097
gwascentral	rs180177097
openSNP	rs180177097
23andMe	rs180177097
SNPshot	rs180177097
SNPdbe	rs180177097
MSV3d	rs180177097
GWAS Ctlg	rs180177097

Max Magnitude

7

ClinVar
Risk	Rs180177097(T;T)
Alt	Rs180177097(T;T)
Reference	Rs180177097(C;C)
Significance	Other
Disease	Familial cancer of breast Pancreatic cancer 3 Breast cancer Hereditary cancer-predisposing syndrome
Variation	info
Gene	PALB2
CLNDBN	Familial cancer of breast Pancreatic cancer 3 Breast cancer, susceptibility to Hereditary cancer-predisposing syndrome
Reversed	1
HGVS	NC_000016.9:g.23646840G>A
CLNSRC	OMIM Allelic Variant PALB2 database
CLNACC	RCV000114452.1, RCV000114453.1, RCV000144519.2, RCV000215551.1,

[PMID 21184274] PALB2 germline mutations in familial breast cancer cases with personal and family history of pancreatic cancer.