rs180177112

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(G;G)	0	common in clinvar
(G;T)	3	increased risk of breast cancer
(T;T)	7	Fanconi anemia, complementation group N

Reference

GRCh38 38.1/141

Chromosome

16

Position

23629768

Gene

PALB2

is a	snp
is	mentioned by
dbSNP	rs180177112
dbSNP (classic)	rs180177112
ClinGen	rs180177112
ebi	rs180177112
HLI	rs180177112
Exac	rs180177112
Gnomad	rs180177112
Varsome	rs180177112
LitVar	rs180177112
Map	rs180177112
PheGenI	rs180177112
Biobank	rs180177112
1000 genomes	rs180177112
hgdp	rs180177112
ensembl	rs180177112
geneview	rs180177112
scholar	rs180177112
google	rs180177112
pharmgkb	rs180177112
gwascentral	rs180177112
openSNP	rs180177112
23andMe	rs180177112
SNPshot	rs180177112
SNPdbe	rs180177112
MSV3d	rs180177112
GWAS Ctlg	rs180177112

Max Magnitude

7

ClinVar
Risk	Rs180177112(T;T)
Alt	Rs180177112(T;T)
Reference	Rs180177112(G;G)
Significance	Other
Disease	Familial cancer of breast Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	PALB2
CLNDBN	Familial cancer of breast Hereditary cancer-predisposing syndrome not provided
Reversed	1
HGVS	NC_000016.9:g.23641089C>A
CLNSRC	PALB2 database
CLNACC	RCV000114524.4, RCV000129116.4, RCV000236024.2,

[PMID 17200668] PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene.

[PMID 21285249] Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer.