rs180177142

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(-;-)	7	Fanconi anemia, complementation group N
(-;G)	3	increased risk of breast cancer
(G;G)	0	common in clinvar

Reference

GRCh38 38.1/141

Chromosome

16

Position

23638106

Gene

PALB2

is a	snp
is	mentioned by
dbSNP	rs180177142
dbSNP (classic)	rs180177142
ClinGen	rs180177142
ebi	rs180177142
HLI	rs180177142
Exac	rs180177142
Gnomad	rs180177142
Varsome	rs180177142
LitVar	rs180177142
Map	rs180177142
PheGenI	rs180177142
Biobank	rs180177142
1000 genomes	rs180177142
hgdp	rs180177142
ensembl	rs180177142
geneview	rs180177142
scholar	rs180177142
google	rs180177142
pharmgkb	rs180177142
gwascentral	rs180177142
openSNP	rs180177142
23andMe	rs180177142
SNPshot	rs180177142
SNPdbe	rs180177142
MSV3d	rs180177142
GWAS Ctlg	rs180177142

Max Magnitude

7

ClinVar
Risk	Rs180177142(-;-)
Alt	Rs180177142(-;-)
Reference	Rs180177142(G;G)
Significance	Pathogenic
Disease	Familial cancer of breast Pancreatic cancer 3 Hereditary cancer-predisposing syndrome
Variation	info
Gene	PALB2
CLNDBN	Familial cancer of breast Pancreatic cancer 3 Hereditary cancer-predisposing syndrome
Reversed	1
HGVS	NC_000016.9:g.23649427delC
CLNSRC	PALB2 database
CLNACC	RCV000114655.1, RCV000114656.1, RCV000164203.1,

[PMID 21184274] PALB2 germline mutations in familial breast cancer cases with personal and family history of pancreatic cancer.