rs1828591

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(A;A)	0	common/normal
(A;G)	1.5	Reduced risk (0.77x) of chronic obstructive pulmonary disease (COPD)
(G;G)	2	Reduced risk (0.54x) for chronic pulmonary obstructive disease (COPD)

Reference

GRCh38 38.1/141

Chromosome

4

Position

144559628

Gene	LOC105377462

is a	snp
is	mentioned by
dbSNP	rs1828591
dbSNP (classic)	rs1828591
ClinGen	rs1828591
ebi	rs1828591
HLI	rs1828591
Exac	rs1828591
Gnomad	rs1828591
Varsome	rs1828591
LitVar	rs1828591
Map	rs1828591
PheGenI	rs1828591
Biobank	rs1828591
1000 genomes	rs1828591
hgdp	rs1828591
ensembl	rs1828591
geneview	rs1828591
scholar	rs1828591
google	rs1828591
pharmgkb	rs1828591
gwascentral	rs1828591
openSNP	rs1828591
23andMe	rs1828591
SNPshot	rs1828591
SNPdbe	rs1828591
MSV3d	rs1828591
GWAS Ctlg	rs1828591

GMAF

0.388

Max Magnitude

2

?	(A;A) (A;G) (G;G)	28

GWAS snp
PMID	[PMID 19300482]
Trait	Chronic Obstructive Pulmonary Disease
Title	A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci
Risk Allele
P-val	1E-7
Odds Ratio	1.38 [1.17-1.63]

[PMID 19300500] A genome-wide association study of pulmonary function measures in the Framingham Heart Study.

[PMID 19996190] Hedgehog-interacting protein is a COPD susceptibility gene: the Rotterdam Study.

[PMID 23886569] Transient early wheeze and lung function in early childhood associated with chronic obstructive pulmonary disease genes

[PMID 23936167] Refining Susceptibility Loci of Chronic Obstructive Pulmonary Disease with Lung eqtls

[PMID 25073350] [Genetic aspects of occupational chronic obstructive lung disease under exposure to various risk factors]

[PMID 28939338] Comparison of the role of HHIP SNPs in susceptibility to chronic obstructive pulmonary disease between Chinese Han and Mongolian populations.