rs200185429
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common/normal |
| (C;T) | 3 | Lower type-2 diabetes risk |
| Make rs200185429(T;T) |
| Reference | GRCh38.p7 38.3/151 |
| Chromosome | 8 |
| Position | 117153084 |
| Gene | LOC105375716, SLC30A8 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs200185429 |
| dbSNP (classic) | rs200185429 |
| ClinGen | rs200185429 |
| ebi | rs200185429 |
| HLI | rs200185429 |
| Exac | rs200185429 |
| Gnomad | rs200185429 |
| Varsome | rs200185429 |
| LitVar | rs200185429 |
| Map | rs200185429 |
| PheGenI | rs200185429 |
| Biobank | rs200185429 |
| 1000 genomes | rs200185429 |
| hgdp | rs200185429 |
| ensembl | rs200185429 |
| geneview | rs200185429 |
| scholar | rs200185429 |
| rs200185429 | |
| pharmgkb | rs200185429 |
| gwascentral | rs200185429 |
| openSNP | rs200185429 |
| 23andMe | rs200185429 |
| SNPshot | rs200185429 |
| SNPdbe | rs200185429 |
| MSV3d | rs200185429 |
| GWAS Ctlg | rs200185429 |
| Max Magnitude | 3 |
rs200185429, also known as c.412C>T, p.Arg138Ter and R138X, is perhaps the best studied of over 10 loss-of-function variants found in the SLC30A8 gene to reduce risk of developing type-2 diabetes by about 2/3rds (OR:0.34, p=1.7×10e−6) in a large Icelandic study published in 2014.[PMID 24584071
]
