rs2061174

Orientation

minus

Stabilized

minus

Make rs2061174(C;C)

Make rs2061174(C;T)

Make rs2061174(T;T)

Reference

GRCh38 38.1/141

Chromosome

7

Position

136976653

Gene	CHRM2, LOC349160

is a	snp
is	mentioned by
dbSNP	rs2061174
dbSNP (classic)	rs2061174
ClinGen	rs2061174
ebi	rs2061174
HLI	rs2061174
Exac	rs2061174
Gnomad	rs2061174
Varsome	rs2061174
LitVar	rs2061174
Map	rs2061174
PheGenI	rs2061174
Biobank	rs2061174
1000 genomes	rs2061174
hgdp	rs2061174
ensembl	rs2061174
geneview	rs2061174
scholar	rs2061174
google	rs2061174
pharmgkb	rs2061174
gwascentral	rs2061174
openSNP	rs2061174
23andMe	rs2061174
SNPshot	rs2061174
SNPdbe	rs2061174
MSV3d	rs2061174
GWAS Ctlg	rs2061174

GMAF

0.4697

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

OMIM	103780
Desc	ALCOHOL DEPENDENCE
Variant
Related	also

OMIM	608516
Desc	MAJOR DEPRESSIVE DISORDER; MDD
Variant
Related	also

OMIM	118493
Desc	CHOLINERGIC RECEPTOR, MUSCARINIC, 2; CHRM2
Variant
Related	also

[PMID 15229186] Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome.

[PMID 17373692] No evidence for association between 19 cholinergic genes and bipolar disorder.

[PMID 17996044] Exploring the functional role of the CHRM2 gene in human cognition: results from a dense genotyping and brain expression study.

[PMID 18634760] Uncovering genes for cognitive (dys)function and predisposition for alcoholism spectrum disorders: a review of human brain oscillations as effective endophenotypes.

[PMID 19181679] Depression Case Control (DeCC) Study fails to support involvement of the muscarinic acetylcholine receptor M2 (CHRM2) gene in recurrent major depressive disorder.