rs2069762
| Orientation | minus |
| Stabilized | minus |
| Make rs2069762(G;G) |
| Make rs2069762(G;T) |
| Make rs2069762(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 4 |
| Position | 122456825 |
| Gene | IL2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2069762 |
| dbSNP (classic) | rs2069762 |
| ClinGen | rs2069762 |
| ebi | rs2069762 |
| HLI | rs2069762 |
| Exac | rs2069762 |
| Gnomad | rs2069762 |
| Varsome | rs2069762 |
| LitVar | rs2069762 |
| Map | rs2069762 |
| PheGenI | rs2069762 |
| Biobank | rs2069762 |
| 1000 genomes | rs2069762 |
| hgdp | rs2069762 |
| ensembl | rs2069762 |
| geneview | rs2069762 |
| scholar | rs2069762 |
| rs2069762 | |
| pharmgkb | rs2069762 |
| gwascentral | rs2069762 |
| openSNP | rs2069762 |
| 23andMe | rs2069762 |
| SNPshot | rs2069762 |
| SNPdbe | rs2069762 |
| MSV3d | rs2069762 |
| GWAS Ctlg | rs2069762 |
| GMAF | 0.247 |
| Max Magnitude | 0 |
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 19058298] Promoter polymorphisms of IL2, IL4, and risk of gastric cancer in a high-risk Chinese population
[PMID 20184734
] The 4q27 locus and familial prostate cancer risk
[PMID 21648020] Haplotype-based analysis of ulcerative colitis risk loci identifies both IL2 and IL21 as susceptibility genes in Han Chinese
| GWAS snp | |
|---|---|
| PMID | [PMID 21829393]
|
| Trait | |
| Title | Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. |
| Risk Allele | A |
| P-val | 5E-7 |
| Odds Ratio | 1.1200 [NR] |
[PMID 22377791] Association of genetic polymorphisms of interleukins with new-onset diabetes after transplantation in renal transplantation
[PMID 16333313] Family based association analysis of the IL2 and IL15 genes in allergic disorders.
[PMID 16449530] Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma.
[PMID 17152005] Associations between measles vaccine immunity and single-nucleotide polymorphisms in cytokine and cytokine receptor genes.
[PMID 17327408] Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival.
[PMID 17355643] Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based population.
[PMID 18598732] Vaccine immunogenetics: bedside to bench to population.
[PMID 18628433] Cervical and vulvar cancer risk in relation to the joint effects of cigarette smoking and genetic variation in interleukin 2.
[PMID 18633131] Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era.
[PMID 19066394] Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma.
[PMID 19126646] Genetic polymorphisms in the cytokine genes and risk of hepatocellular carcinoma in low-risk non-Asians of USA.
[PMID 19147066] Genomic and proteomic analysis of allogeneic hematopoietic cell transplant outcome. Seeking greater understanding the pathogenesis of GVHD and mortality.
[PMID 19173720] Low frequency of CD4+CD25+ Treg in SLE patients: a heritable trait associated with CTLA4 and TGFbeta gene variants.
[PMID 19356949] Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies.
[PMID 19450131] Application of pharmacogenomics to vaccines.
[PMID 19523143] Multiple sclerosis association study with the TENR-IL2-IL21 region in a Spanish population.
[PMID 20811626] Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.
[PMID 21649724] Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country.
[PMID 21875636] Associations between single nucleotide polymorphisms and haplotypes in cytokine and cytokine receptor genes and immunity to measles vaccination.
[PMID 23172754] Implication of IL-2/IL-21 region in systemic sclerosis genetic susceptibility
[PMID 23487197] Association of Interleukin 2 (IL-2), Interleukin 6 (IL-6), and TNF-alpha (TNFα) Gene Polymorphisms With Paranoid Schizophrenia in a Polish Population
[PMID 25037274] Autoimmune diseases association study with the KIAA1109-IL2-IL21 region in a Tunisian population
[PMID 26550166] Lack of association between interleukin-2 (IL-2) gene rs2069762 polymorphism and cancer risk: a meta-analysis
[PMID 31519598] Genetic Variants of the IL2 Gene Related to Risk and Survival in Patients With Colorectal Cancer.
[PMID 32425678] Polymorphisms of genes encoding cytokines predict the risk of high-grade bladder cancer and outcomes of BCG immunotherapy.
[PMID 32432788] Effects of gene polymorphism and serum levels of IL-2 and IL-6 on endometriosis.
