| Geno
|
Mag
|
Summary
|
| (G;G)
|
|
age at menarche ~2 months later on average
|
| (G;T)
|
|
age at menarche ~1 month later on average
|
| (T;T)
|
|
normal
|
rs2090409 is a SNP from chromosomal region 9q31.2 showing the strongest association with age at menarche in a study of 17,500 Icelandic women.
Per copy carried of the rs2090409(A) allele, age at menarche is delayed about 1 month.
| GWAS snp
|
| PMID
|
[PMID 19448620 ]
|
| Trait
|
Menarche
|
| Title
|
Meta-analysis of genome-wide association data identifies two loci influencing age at menarche
|
| Risk Allele
|
A
|
| P-val
|
2E-9
|
| Odds Ratio
|
0.10 [0.06-0.14] years younger
|
| GWAS snp
|
| PMID
|
[PMID 21102462]
|
| Trait
|
|
| Title
|
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies
|
| Risk Allele
|
A
|
| P-val
|
2E-33
|
| Odds Ratio
|
4.7000 [3.92-5.48] week decrease
|
| GWAS snp
|
| PMID
|
[PMID 23449627]
|
| Trait
|
Pubertal anthropometrics
|
| Title
|
Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.
|
| Risk Allele
|
C
|
| P-val
|
2E-6
|
| Odds Ratio
|
.11 [0.065-0.155] unit increase
|
]
