rs2227284
| Orientation | minus |
| Stabilized | minus |
| Make rs2227284(A;A) |
| Make rs2227284(A;C) |
| Make rs2227284(C;C) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 5 |
| Position | 132677033 |
| Gene | IL4 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2227284 |
| dbSNP (classic) | rs2227284 |
| ClinGen | rs2227284 |
| ebi | rs2227284 |
| HLI | rs2227284 |
| Exac | rs2227284 |
| Gnomad | rs2227284 |
| Varsome | rs2227284 |
| LitVar | rs2227284 |
| Map | rs2227284 |
| PheGenI | rs2227284 |
| Biobank | rs2227284 |
| 1000 genomes | rs2227284 |
| hgdp | rs2227284 |
| ensembl | rs2227284 |
| geneview | rs2227284 |
| scholar | rs2227284 |
| rs2227284 | |
| pharmgkb | rs2227284 |
| gwascentral | rs2227284 |
| openSNP | rs2227284 |
| 23andMe | rs2227284 |
| SNPshot | rs2227284 |
| SNPdbe | rs2227284 |
| MSV3d | rs2227284 |
| GWAS Ctlg | rs2227284 |
| GMAF | 0.4008 |
| Max Magnitude | 0 |
| ? | (A;A) (A;C) (C;C) | 28 |
|---|---|---|
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[PMID 20403914] Comprehensive analysis of the cytokine rich chromosome 5q31.1 region suggests a role for IL-4 gene variants in prostate cancer risk
[PMID 15570643] Epistatic interactions between HLA-DRB1 and interleukin 4, but not interferon-gamma, increase susceptibility to giant cell arteritis.
[PMID 15660293
] No evidence of association or interaction between the IL4RA, IL4, and IL13 genes in type 1 diabetes.
[PMID 18056382] Analysis of the 5q31 33 locus shows an association between single nucleotide polymorphism variants in the IL-5 gene and symptomatic infection with the human blood fluke, Schistosoma japonicum.
[PMID 18625055] Lack of association or interactions between the IL-4, IL-4Ralpha and IL-13 genes, and rheumatoid arthritis.
[PMID 19956101] Overview of the Rapid Response data.
[PMID 20015396] Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians.
[PMID 21387019] Differences in candidate gene association between European ancestry and African American asthmatic children.
[PMID 23651591] Association of polymorphisms in the interleukin-4 gene with response to hepatitis B vaccine and susceptibility to hepatitis B virus infection: a meta-analysis
[PMID 23654077] IL-4 gene polymorphisms and their association with atopic asthma and allergic rhinitis in Pakistani patients
[PMID 23964553] Relationship between polymorphisms in IL4 and asthma in Japanese women: the Kyushu Okinawa Maternal and Child Health Study
[PMID 22824342] Association of polymorphisms of cytokine and TLR-2 genes with long-term immunity to hepatitis B in children vaccinated early in life.
[PMID 22884982] Polymorphisms in the IL4 gene, smoking, and rhinoconjunctivitis in Japanese women: the Kyushu Okinawa Maternal and Child Health Study.
[PMID 23663310] Investigating highly replicated asthma genes as candidate genes for allergic rhinitis.
[PMID 24502445] Cytokine candidate genes predict the development of secondary lymphedema following breast cancer surgery
[PMID 25785117] Associations between polymorphisms in the IL-4 and IL-4 receptor genes and urinary carcinomas: a meta-analysis
[PMID 26426602] Polymorphisms in the interleukin 4, interleukin 4 receptor and interleukin 13 genes and allergic phenotype: A case control study
[PMID 29407193] Genetic susceptibility to invasive pneumococcal disease.
