rs2228314

plus

Geno	Mag	Summary
(C;C)	2	2.03x risk of osteoarthritis
(C;G)	1.4	1.48x risk of osteoarthritis
(G;G)	1	No increased risk of osteoarthritis

Reference

GRCh38 38.1/141

Chromosome

22

Position

41880738

Gene

SREBF2

is a	snp
is	mentioned by
dbSNP	rs2228314
dbSNP (classic)	rs2228314
ClinGen	rs2228314
ebi	rs2228314
HLI	rs2228314
Exac	rs2228314
Gnomad	rs2228314
Varsome	rs2228314
LitVar	rs2228314
Map	rs2228314
PheGenI	rs2228314
Biobank	rs2228314
1000 genomes	rs2228314
hgdp	rs2228314
ensembl	rs2228314
geneview	rs2228314
scholar	rs2228314
google	rs2228314
pharmgkb	rs2228314
gwascentral	rs2228314
openSNP	rs2228314
23andMe	rs2228314
SNPshot	rs2228314
SNPdbe	rs2228314
MSV3d	rs2228314
GWAS Ctlg	rs2228314

Merged from

0.3664

2

(C;C) (C;G) (G;G)

28

[PMID 22662110 ] Central Role of SREBP-2 in the Pathogenesis of Osteoarthritis. Heterozygous odds ratio 1.481 (1.201–1.827) p<0.001; Homozygous minor odds ratio 2.038 (0.693–5.992) p = 0.187

[PMID 20111910] Sterol regulatory element-binding transcription factor (SREBF)-2, SREBF cleavage-activating protein (SCAP), and premature coronary artery disease in a Chinese population

[PMID 19116028 ] Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death.

[PMID 19740467] Interactions among genetic variants from SREBP2 activating-related pathway on risk of coronary heart disease in Chinese Han population.

[PMID 24992162] Relationship of SREBP-2 rs2228314 G>C Polymorphism with Nonalcoholic Fatty Liver Disease in a Han Chinese Population

[PMID 25005769] Association Between Single Nucleotide Polymorphisms of Sterol Regulatory Element Binding Protein-2 and Liver X Receptor α Gene and Risk of Polycystic Ovary Syndrome in a Chinese Han Population

[PMID 31490983 ] SREBF1c and SREBF2 gene polymorphisms are associated with acute coronary syndrome and blood lipid levels in Mexican population.