| Rs2240335
|
| PubMed
|
[PMID 12833157]
|
| Affy Probeset
|
SNP_A-8556874
|
| Affy Orientation
|
same
|
| On GW 5.0
|
0
|
| Alleles A/B
|
G/T
|
| Ancestral
|
G
|
| Population
|
Japan
|
| Allele
|
G
|
| Case Freq.
|
|
| Control Freq.
|
|
| Odds Ratio Het
|
|
| Odds Ratio Hom
|
|
| Odds Ratio All
|
1.75
|
| Disease
|
Rheumatoid Arthritis (RA)
|
rs2240335 is in linkage disequilibrium with a polymorphism that increases susceptibility to Rheumatoid Arthritis 1.75 times for carriers of the G allele [PMID 12833157]
| GWAS snp
|
| PMID
|
[PMID 21225715]
|
| Trait
|
|
| Title
|
Genome-wide association study of rheumatoid arthritis in Korea: Population-specific loci as well as overlap with European susceptibility loci
|
| Risk Allele
|
|
| P-val
|
2E-8
|
| Odds Ratio
|
1.5000 [NR]
|
| GWAS snp
|
| PMID
|
[PMID 21505073]
|
| Trait
|
|
| Title
|
The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.
|
| Risk Allele
|
|
| P-val
|
2E-8
|
| Odds Ratio
|
None None
|
| GWAS snp
|
| PMID
|
[PMID 21452313]
|
| Trait
|
|
| Title
|
Genome-wide association study of rheumatoid arthritis in Koreans: population-specific loci as well as overlap with European susceptibility loci.
|
| Risk Allele
|
|
| P-val
|
2E-8
|
| Odds Ratio
|
1.5000 [NR]
|
[PMID 29425503] Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility.
