rs2395029(G;T)

HLA-B*5701 carrier most likely (if Caucasian or Hispanic)

Is a	genotype
of	rs2395029
Gene	HCP5
Chromosome	6
Position	31,464,003
mentioned	by

Magnitude

3.2

Repute

Bad

Geno	Mag	Summary
(G;G)	4	HLA-B*5701 homozygote likely if Caucasian or Hispanic; high risk for hypersensitivity to various drugs including abacavir; 2x psoriasis risk; see details
(G;T)	3.2	HLA-B*5701 carrier most likely (if Caucasian or Hispanic)
(T;T)	0	common

risk for hypersensitivity to various drugs including abacavir

This genotype is associated with an HIV viral load 1 log (10 fold) lower than the most common genotype (rs2395029(T;T)). [PMID 17641165]

Possible 2x higher risk for psoriasis

See also rs2395029 and HIV.

The (G) allele frequency is only 0.05 which means only about 1 in 10 people have this genotype.