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From SNPedia

Make rs2430561(A;A)
Make rs2430561(A;T)
Make rs2430561(T;T)
ReferenceGRCh38 38.1/141
is asnp
is mentioned by
dbSNP (classic)rs2430561
1000 genomesrs2430561
23andMe allrs2430561
GWAS Ctlgrs2430561
Merged fromRs61923114
Max Magnitude0

[PMID 19386798OA-icon.png] Relevance of gamma interferon, tumor necrosis factor alpha, and interleukin-10 gene polymorphisms to susceptibility to Mediterranean spotted fever

[PMID 19733878] Interferon-gamma 874A>T genetic polymorphism is associated with infectious complications following surgery in patients with thoracic esophageal cancer

[PMID 19919944] Interferon-gamma gene polymorphisms associated with susceptibility to systemic lupus erythematosus

[PMID 20714752] IFNG +874 T>A single nucleotide polymorphism is associated with leprosy among Brazilians

[PMID 21204904] The relationship between interferon-? gene polymorphism and acute kidney allograft rejection

[PMID 21728784] The T allele of the interferon-gamma +874A/T polymorphism is associated with bipolar disorder

[PMID 22041017] Association of interferon-gamma gene polymorphisms with susceptibility to oral lichen planus in the Thai population

[PMID 22189538] Polymorphisms of the Interferon gamma gene and coronary artery disease in the Korean population

[PMID 16493441] Role of interferon-gamma gene polymorphisms in susceptibility to IgA nephropathy: a family-based association study.

[PMID 16504056OA-icon.png] Polymorphism discovery and association analyses of the interferon genes in type 1 diabetes.

[PMID 16672072OA-icon.png] The interferon gamma gene polymorphism +874 A/T is associated with severe acute respiratory syndrome.

[PMID 17136124OA-icon.png] IFNG and IFNGR1 gene polymorphisms and susceptibility to post-kala-azar dermal leishmaniasis in Sudan.

[PMID 17215375OA-icon.png] A functional SNP of interferon-gamma gene is important for interferon-alpha-induced and spontaneous recovery from hepatitis C virus infection.

[PMID 17705862OA-icon.png] Optimization of candidate-gene SNP-genotyping by flexible oligonucleotide microarrays; analyzing variations in immune regulator genes of hay-fever samples.

[PMID 17994425] Interleukin (IL)-12, IL-2, interferon-gamma gene polymorphisms in subacute sclerosing panencephalitis patients.

[PMID 18041006] Association of TGF-beta1 codon 25 (G915C) polymorphism with hepatitis C virus infection.

[PMID 18062835OA-icon.png] Novel insight in the association between salmonellosis or campylobacteriosis and chronic illness, and the role of host genetics in susceptibility to these diseases.

[PMID 18199975] Polymorphism of IFN-gamma gene and Vogt-Koyanagi-Harada disease.

[PMID 18307517OA-icon.png] Common studied polymorphisms do not affect plasma cytokine levels upon endotoxin exposure in humans.

[PMID 19478423OA-icon.png] Cytokine response to vitamin E supplementation is dependent on pre-supplementation cytokine levels.

[PMID 20196868OA-icon.png] Polymorphisms in IL-1beta, vitamin D receptor Fok1, and Toll-like receptor 2 are associated with extrapulmonary tuberculosis.

[PMID 20359550OA-icon.png] Role of the IFNG +874T/A polymorphism in Chagas disease in a Colombian population.

[PMID 20544370] Association of genetic polymorphisms in the IL12-IFNG pathway with susceptibility to and prognosis of pulmonary tuberculosis in a Chinese population.

[PMID 20811626OA-icon.png] Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.

[PMID 21332391] Interferon gamma +874T/A polymorphism is associated with susceptibility to active pulmonary tuberculosis development in Tunisian patients.

[PMID 21562768] A study of the impact of cytokine gene polymorphism in acute rejection of renal transplant recipients.

[PMID 21798578OA-icon.png] IFNG genotype and sex interact to influence the risk of childhood asthma.

[PMID 22372709] Cytokine gene polymorphisms in the susceptibility to acute coronary syndrome.

[PMID 22392581] Genetic variants of the MRC1 gene and the IFNG gene are associated with leprosy in Han Chinese from Southwest China.

[PMID 22624006OA-icon.png] Joint Effects of Febrile Acute Infection and an Interferon-γ Polymorphism on Breast Cancer Risk

[PMID 23077565OA-icon.png] Analysis of the Interferon Gamma (rs2430561, +874T/A) Functional Gene Variant in Relation to the Presence of Cardiovascular Events in Rheumatoid Arthritis

[PMID 23737189] IFNG polymorphisms are associated with tuberculosis in Han Chinese pediatric female population

[PMID 23803376] Polymorphisms of Interferon Gamma Gene and Risk of Hepatocellular Carcinoma in Korean Patients with Chronic Hepatitis B Viral Infection

[PMID 24075848] The gene-immune-behavioral pathway: Gamma-interferon (IFN-γ) simultaneously coordinates susceptibility to infectious disease and harm avoidance behaviors

[PMID 24167151] Polymorphism of the rs1800896 IL10 promoter gene protects children from post-bronchiolitis asthma

[PMID 23061992] Association of interferon gamma polymorphism with ossification of the posterior longitudinal ligament in the korean population.

[PMID 23133602OA-icon.png] Pharmacogenetics of efficacy and safety of HCV treatment in HCV-HIV coinfected patients: significant associations with IL28B and SOCS3 gene variants.

[PMID 23159874] Pro-inflammatory cytokine gene polymorphisms and threat for coronary heart disease in a North Indian Agrawal population.

[PMID 23777204OA-icon.png] Involvement of interferon-gamma genetic variants and intercellular adhesion molecule-1 in onset and progression of generalized vitiligo.

[PMID 24008079OA-icon.png] Cytokine gene polymorphisms and progression-free survival in classical Hodgkin lymphoma by EBV status: results from two independent cohorts

[PMID 24967817OA-icon.png] Anti-TNF Treatment Response in Rheumatoid Arthritis Patients Is Associated with Genetic Variation in the NLRP3-Inflammasome

[PMID 25051917] Correlations of IFN-γ genetic polymorphisms with susceptibility to breast cancer: a meta-analysis

[PMID 25445652] Interferon-γ (IFNG) microsatellite repeat and single nucleotide polymorphism haplotypes of IFN-α receptor (IFNAR1) associated with enhanced malaria susceptibility in Indian populations

[PMID 25649976] Interferon gamma +874 T/A polymorphism increases the risk of cervical cancer: evidence from a meta-analysis

[PMID 26313134] Evidence of an IFN-γ by early life stress interaction in the regulation of amygdala reactivity to emotional stimuli

[PMID 26458193] Association between IFN-γ genetic polymorphisms and susceptibility to hepatitis B virus infection: a meta-analysis

[PMID 24776844] Associations between functional polymorphisms in the NFκB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease

[PMID 27819519] Association of the IFN-γ (+874A/T) Genetic Polymorphism with Paranoid Schizophrenia in Tunisian Population.

[PMID 28739396] Genetic association of pro-inflammatory cytokine gene polymorphisms with coronary artery disease (CAD) in a North Indian population.

[PMID 30100739OA-icon.png] Polymorphism of IFN-γ +874T/A associated with production of IFN-γ affects human papillomavirus susceptibility in rural women from Luohe, Henan, China.