rs2837960
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 2.3 | 2.3x rheumatoid arthritis risk |
| (G;T) | 0 | normal |
| (T;T) | 0 | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 21 |
| Position | 41139991 |
| Gene | LINC00323 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2837960 |
| dbSNP (classic) | rs2837960 |
| ClinGen | rs2837960 |
| ebi | rs2837960 |
| HLI | rs2837960 |
| Exac | rs2837960 |
| Gnomad | rs2837960 |
| Varsome | rs2837960 |
| LitVar | rs2837960 |
| Map | rs2837960 |
| PheGenI | rs2837960 |
| Biobank | rs2837960 |
| 1000 genomes | rs2837960 |
| hgdp | rs2837960 |
| ensembl | rs2837960 |
| geneview | rs2837960 |
| scholar | rs2837960 |
| rs2837960 | |
| pharmgkb | rs2837960 |
| gwascentral | rs2837960 |
| openSNP | rs2837960 |
| 23andMe | rs2837960 |
| SNPshot | rs2837960 |
| SNPdbe | rs2837960 |
| MSV3d | rs2837960 |
| GWAS Ctlg | rs2837960 |
| GMAF | 0.2071 |
| Max Magnitude | 2.3 |
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs2837960 has been reported in a large study to be associated with rheumatoid arthritis.
The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 0.95 (CI 0.83-1.08), and for homozygotes, 2.30 (CI 1.64-3.23). [PMID 17554300
]
| GWAS | |
|---|---|
| SNP | rs2837960 |
| PubMedID | [PMID 17554300]
|
| Condition | Rheumatoid arthritis |
| Gene | NR |
| Risk Allele | G |
| pValue | 2.00E-006 |
| OR | 1.05 |
| 95% CI | 0.93-1.20 |
[PMID 21595938] Rheumatoid arthritis-associated polymorphisms are not protective against Alzheimer's disease
[PMID 18794857] Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.
[PMID 20017963] Representation of genetic association via attributable familial relative risks in order to identify polymorphisms functionally relevant to rheumatoid arthritis.
[PMID 20426808] AntEpiSeeker: detecting epistatic interactions for case-control studies using a two-stage ant colony optimization algorithm.
