rs2943634

plus

Geno	Mag	Summary
(A;A)	2.5	lower risk of ischemic stroke
(C;C)	2.5	slightly higher risk of ischemic stroke

Make rs2943634(A;C)

Reference

GRCh38 38.1/141

Chromosome

2

Position

226203364

is a	snp
is	mentioned by
dbSNP	rs2943634
dbSNP (classic)	rs2943634
ClinGen	rs2943634
ebi	rs2943634
HLI	rs2943634
Exac	rs2943634
Gnomad	rs2943634
Varsome	rs2943634
LitVar	rs2943634
Map	rs2943634
PheGenI	rs2943634
Biobank	rs2943634
1000 genomes	rs2943634
hgdp	rs2943634
ensembl	rs2943634
geneview	rs2943634
scholar	rs2943634
google	rs2943634
pharmgkb	rs2943634
gwascentral	rs2943634
openSNP	rs2943634
23andMe	rs2943634
SNPshot	rs2943634
SNPdbe	rs2943634
MSV3d	rs2943634
GWAS Ctlg	rs2943634

GMAF

0.3214

Max Magnitude

2.5

?

(A;A) (A;C) (C;C)

28

rs2943634 is a SNP found to be reproducibly associated with heart disease [PMID 17634449 ] [PMID 18979498 ] rs2943634 associated with high density lipoprotein (HDL) cholesterol

GWAS
SNP	rs2943634
PubMedID	[PMID 17634449 ]
Condition	Coronary disease
Gene	pseudogene
Risk Allele	C
pValue	2.00E-007
OR	1.21
95% CI	1.13-1.30

[PMID 19164808 ] Large scale association analysis of novel genetic loci for coronary artery disease

[PMID 18675980 ] Novel genetic variants linked to coronary artery disease by genome-wide association are not associated with carotid artery intima-media thickness or intermediate risk phenotypes

[PMID 19373437] Association of three polymorphisms selected from a genome-wide association study with coronary heart disease in the Tunisian population

[PMID 21463265 ] Association of SNP rs17465637 on Chromosome 1q41 and rs599839 on 1p13.3 with Myocardial Infarction in an American Caucasian Population

[PMID 22207032] Significant associations of the rs2943634 (2q36.3) genetic polymorphism with adiponectin, high density lipoprotein cholesterol and ischemic stroke

[PMID 18780302 ] Association studies of 22 candidate SNPs with late-onset Alzheimer's disease.

[PMID 19135198] Evaluation of the association of genetic variants on the chromosomal loci 9p21.3, 6q25.1, and 2q36.3 with angiographically characterized coronary artery disease.

[PMID 19198609 ] Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.

[PMID 19750184 ] Genome-wide association studies for atherosclerotic vascular disease and its risk factors.

[PMID 19956433 ] Genetics of coronary artery disease: focus on genome-wide association studies.

[PMID 20017983 ] Evaluation of population impact of candidate polymorphisms for coronary heart disease in the Framingham Heart Study Offspring Cohort.

[PMID 21804106 ] Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration.

[PMID 22042884 ] Association of genetic variants and incident coronary heart disease in multiethnic cohorts: the PAGE study.

GWAS snp
PMID	[PMID 22581228 ]
Trait
Title	A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
Risk Allele
P-val	2E-14
Odds Ratio	None None

[PMID 23101478 ] Single nucleotide polymorphisms (SNPs) involved in insulin resistance, weight regulation, lipid metabolism and inflammation in relation to metabolic syndrome: an epidemiological study

[PMID 23659870 ] Common variants in and near IRS1 and subclinical cardiovascular disease in the Framingham Heart Study

[PMID 22797928] Evidence of selection at insulin receptor substrate-1 gene loci.

[PMID 28674662 ] BMI prediction within a Korean population.