rs3025786
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 1.6 | slightly decreased Alzheimer's disease risk among ApoE4 carriers |
| (C;T) | 1.6 | slightly decreased Alzheimer's disease risk among ApoE4 carriers |
| (T;T) | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 14 |
| Position | 73198010 |
| Gene | PSEN1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3025786 |
| dbSNP (classic) | rs3025786 |
| ClinGen | rs3025786 |
| ebi | rs3025786 |
| HLI | rs3025786 |
| Exac | rs3025786 |
| Gnomad | rs3025786 |
| Varsome | rs3025786 |
| LitVar | rs3025786 |
| Map | rs3025786 |
| PheGenI | rs3025786 |
| Biobank | rs3025786 |
| 1000 genomes | rs3025786 |
| hgdp | rs3025786 |
| ensembl | rs3025786 |
| geneview | rs3025786 |
| scholar | rs3025786 |
| rs3025786 | |
| pharmgkb | rs3025786 |
| gwascentral | rs3025786 |
| openSNP | rs3025786 |
| 23andMe | rs3025786 |
| SNPshot | rs3025786 |
| SNPdbe | rs3025786 |
| MSV3d | rs3025786 |
| GWAS Ctlg | rs3025786 |
| GMAF | 0.02893 |
| Max Magnitude | 1.6 |
rs3025786 is a SNP in the presenilin 1 PSEN1 gene.
A study of a Spanish case-control sample of 1,183 individuals showed rs3025786 was associated with Alzheimer's disease in an ApoE-specific manner: more specifically rs3025786(C) allele carriers have a decreased AD risk among carriers of the ApoE4 allele. [PMID 18957849]
