rs3095318
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common/normal |
| (A;T) | 3 | In Japanese populations, associated with HLA-B*5801 allele and allopurinol side effects |
| (T;T) | 3 | In Japanese populations, associated with HLA-B*5801 allele and allopurinol side effects |
| Reference | GRCh37.p5 37.3/135 |
| Chromosome | 6 |
| Position | 31120368 |
| Gene | CDSN, PSORS1C1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3095318 |
| dbSNP (classic) | rs3095318 |
| ClinGen | rs3095318 |
| ebi | rs3095318 |
| HLI | rs3095318 |
| Exac | rs3095318 |
| Gnomad | rs3095318 |
| Varsome | rs3095318 |
| LitVar | rs3095318 |
| Map | rs3095318 |
| PheGenI | rs3095318 |
| Biobank | rs3095318 |
| 1000 genomes | rs3095318 |
| hgdp | rs3095318 |
| ensembl | rs3095318 |
| geneview | rs3095318 |
| scholar | rs3095318 |
| rs3095318 | |
| pharmgkb | rs3095318 |
| gwascentral | rs3095318 |
| openSNP | rs3095318 |
| 23andMe | rs3095318 |
| SNPshot | rs3095318 |
| SNPdbe | rs3095318 |
| MSV3d | rs3095318 |
| GWAS Ctlg | rs3095318 |
| GMAF | 0.1172 |
| Max Magnitude | 3 |
The minor allele rs3095318(T), as defined on the minus strand, is reported to be associated in Japanese populations with the HLA-B*5801 allele and therefore susceptibility to severe side effects from taking allopurinol and perhaps other drugs. [PMID 16998491
]
[PMID 16642438] Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene.
