rs3114018

plus

Geno	Mag	Summary
(A;A)	0	common/normal
(A;C)	2.3	Somewhat higher risk for gout among Chinese
(C;C)	2.3	Somewhat higher risk for gout among Chinese

Reference

GRCh38 38.1/141

Chromosome

4

Position

88143429

Gene

ABCG2

is a	snp
is	mentioned by
dbSNP	rs3114018
dbSNP (classic)	rs3114018
ClinGen	rs3114018
ebi	rs3114018
HLI	rs3114018
Exac	rs3114018
Gnomad	rs3114018
Varsome	rs3114018
LitVar	rs3114018
Map	rs3114018
PheGenI	rs3114018
Biobank	rs3114018
1000 genomes	rs3114018
hgdp	rs3114018
ensembl	rs3114018
geneview	rs3114018
scholar	rs3114018
google	rs3114018
pharmgkb	rs3114018
gwascentral	rs3114018
openSNP	rs3114018
23andMe	rs3114018
SNPshot	rs3114018
SNPdbe	rs3114018
MSV3d	rs3114018
GWAS Ctlg	rs3114018

GMAF

0.4862

Max Magnitude

2.3

rs3114018(C), a variant in the ABCG2 gene, was the most significantly associated with gout in a 2017 study of ~200 Han Chinese patients (OR 3.19, CI:2.24–4.55, p=6.1x10e-11). This study also defined 5 haplotype blocks associated with gout.[PMID 28855613 ]

?

(A;A) (A;C) (C;C)

28

GWAS snp
PMID	[PMID 23064961 ]
Trait	Dental caries
Title	GWAS of Dental Caries Patterns in the Permanent Dentition.
Risk Allele
P-val	7E-8
Odds Ratio	NR NR

[PMID 24351404] Pharmacogenetic predictors of severe peripheral neuropathy in colon cancer patients treated with oxaliplatin-based adjuvant chemotherapy: a GEMCAD group study

GWAS snp
PMID	[PMID 24513273 ]
Trait	Serum uric acid levels
Title	A genome-wide association study identifies common variants influencing serum uric acid concentrations in a Chinese population.
Risk Allele	T
P-val	4E-20
Odds Ratio	.03 [0.021-0.037] unit decrease

[PMID 26506822] Genetic variation in the ABCG2 gene is associated with gout risk in the Chinese Han population