rs3212236
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | higher risk for dyslexia | |
| (A;G) | normal risk | |
| (C;T) | 0 | |
| (G;G) | normal risk |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 24648227 |
| Gene | TTRAP |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3212236 |
| dbSNP (classic) | rs3212236 |
| ClinGen | rs3212236 |
| ebi | rs3212236 |
| HLI | rs3212236 |
| Exac | rs3212236 |
| Gnomad | rs3212236 |
| Varsome | rs3212236 |
| LitVar | rs3212236 |
| Map | rs3212236 |
| PheGenI | rs3212236 |
| Biobank | rs3212236 |
| 1000 genomes | rs3212236 |
| hgdp | rs3212236 |
| ensembl | rs3212236 |
| geneview | rs3212236 |
| scholar | rs3212236 |
| rs3212236 | |
| pharmgkb | rs3212236 |
| gwascentral | rs3212236 |
| openSNP | rs3212236 |
| 23andMe | rs3212236 |
| SNPshot | rs3212236 |
| SNPdbe | rs3212236 |
| MSV3d | rs3212236 |
| GWAS Ctlg | rs3212236 |
| GMAF | 0.3287 |
| Max Magnitude | 0 |
The more common allele of rs3212236 has been linked to increased risk for developmental dyslexia in a study of ~300 British families. While odds ratios were not reported, the significance was reported as p=0.02.[PMID 17033633]
[PMID 15717286
] Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia.
[PMID 19325871] A common variant associated with dyslexia reduces expression of the KIAA0319 gene.
