rs339097
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (T;T) | 0 | common in complete genomics |
| Make rs339097(C;C) |
| Make rs339097(C;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 7 |
| Position | 128759170 |
| Gene | CALU |
| is a | snp |
| is | mentioned by |
| dbSNP | rs339097 |
| dbSNP (classic) | rs339097 |
| ClinGen | rs339097 |
| ebi | rs339097 |
| HLI | rs339097 |
| Exac | rs339097 |
| Gnomad | rs339097 |
| Varsome | rs339097 |
| LitVar | rs339097 |
| Map | rs339097 |
| PheGenI | rs339097 |
| Biobank | rs339097 |
| 1000 genomes | rs339097 |
| hgdp | rs339097 |
| ensembl | rs339097 |
| geneview | rs339097 |
| scholar | rs339097 |
| rs339097 | |
| pharmgkb | rs339097 |
| gwascentral | rs339097 |
| openSNP | rs339097 |
| 23andMe | rs339097 |
| SNPshot | rs339097 |
| SNPdbe | rs339097 |
| MSV3d | rs339097 |
| GWAS Ctlg | rs339097 |
| GMAF | 0.04545 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
PharmGKB indicates that this SNP is relevant to Warfarin dosing. rs339097(G) is associated with 14.5% higher therapeutic warfarin dose in African Americans. This variant is also more common in African Americans with minor allele frequencies of 11–14% , but only 0.2% in Caucasians.
[PMID 21228733
] Genetic and nongenetic factors associated with warfarin dose requirements in Egyptian patients.
[PMID 22676711] Pharmacogenomics of warfarin in populations of African descent.
| ClinVar | |
|---|---|
| Risk | rs339097(C;C) |
| Alt | rs339097(C;C) |
| Reference | Rs339097(T;T) |
| Significance | Drug-response |
| Disease | warfarin response - Dosage |
| Variation | info |
| Gene | CALU |
| CLNDBN | warfarin response - Dosage |
| Reversed | 1 |
| HGVS | NC_000007.13:g.128399224A>G |
| CLNSRC | PharmGKB Clinical Annotation |
| CLNACC | RCV000211348.1, |
