rs35808389

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(A;A)	0	common in clinvar
(A;G)	6.5	Parkinson's disease mutation, adult-onset

Make rs35808389(G;G)

Reference

GRCh38 38.1/141

Chromosome

12

Position

40298488

Gene

LRRK2

is a	snp
is	mentioned by
dbSNP	rs35808389
dbSNP (classic)	rs35808389
ClinGen	rs35808389
ebi	rs35808389
HLI	rs35808389
Exac	rs35808389
Gnomad	rs35808389
Varsome	rs35808389
LitVar	rs35808389
Map	rs35808389
PheGenI	rs35808389
Biobank	rs35808389
1000 genomes	rs35808389
hgdp	rs35808389
ensembl	rs35808389
geneview	rs35808389
scholar	rs35808389
google	rs35808389
pharmgkb	rs35808389
gwascentral	rs35808389
openSNP	rs35808389
23andMe	rs35808389
SNPshot	rs35808389
SNPdbe	rs35808389
MSV3d	rs35808389
GWAS Ctlg	rs35808389

Max Magnitude

6.5

c.3342A>G (p.Leu1114=)

ClinVar
Risk	rs35808389(G;G)
Alt	rs35808389(G;G)
Reference	Rs35808389(A;A)
Significance	Pathogenic
Disease	Parkinson disease 8
Variation	info
Gene	LRRK2
CLNDBN	Parkinson disease 8, autosomal dominant
Reversed	0
HGVS	NC_000012.11:g.40692290A>G
CLNSRC	ClinVar GeneReviews
CLNACC	RCV000032438.1,

[PMID 15541309] Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology.