rs3733402

plus

Geno	Mag	Summary
(G;G)	0	common in clinvar

Make rs3733402(A;A)

Make rs3733402(A;G)

Reference

GRCh38 38.1/141

Chromosome

4

Position

186236880

Gene

KLKB1

is a	snp
is	mentioned by
dbSNP	rs3733402
dbSNP (classic)	rs3733402
ClinGen	rs3733402
ebi	rs3733402
HLI	rs3733402
Exac	rs3733402
Gnomad	rs3733402
Varsome	rs3733402
LitVar	rs3733402
Map	rs3733402
PheGenI	rs3733402
Biobank	rs3733402
1000 genomes	rs3733402
hgdp	rs3733402
ensembl	rs3733402
geneview	rs3733402
scholar	rs3733402
google	rs3733402
pharmgkb	rs3733402
gwascentral	rs3733402
openSNP	rs3733402
23andMe	rs3733402
SNPshot	rs3733402
SNPdbe	rs3733402
MSV3d	rs3733402
GWAS Ctlg	rs3733402

GMAF

0.3719

Max Magnitude

0

OMIM	229000
Desc
Variant	0005
Related	also

ClinVar
Risk	rs3733402(A;A) rs3733402(C;C)
Alt	rs3733402(A;A) rs3733402(C;C)
Reference	Rs3733402(G;G)
Significance	Pathogenic
Disease	Prekallikrein deficiency
Variation	info
Gene	KLKB1
CLNDBN	Prekallikrein deficiency
Reversed	0
HGVS	NC_000004.11:g.187158034G>A
CLNSRC	OMIM Allelic Variant
CLNACC	RCV000012817.25,

GWAS snp
PMID	[PMID 23251661 ]
Trait	Obesity-related traits
Title	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
Risk Allele	G
P-val	9E-8
Odds Ratio	.04 [NR] ng/mL increase

GWAS snp
PMID	[PMID 24625756 ]
Trait	Serum metabolite levels
Title	Genetic determinants influencing human serum metabolome among African Americans.
Risk Allele	A
P-val	9E-27
Odds Ratio	.44 [NR] unit increase

[PMID 27656708 ] Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels.