rs403016
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 2 | normal |
| (C;G) | 2 | 2x risk for lupus |
| (G;G) | 2 | 2x risk for lupus |
| Reference | GRCh37 37.1/131 |
| Chromosome | 1 |
| Position | 161548632 |
| Gene | FCGR3A |
| is a | snp |
| is | mentioned by |
| dbSNP | rs403016 |
| dbSNP (classic) | rs403016 |
| ClinGen | rs403016 |
| ebi | rs403016 |
| HLI | rs403016 |
| Exac | rs403016 |
| Gnomad | rs403016 |
| Varsome | rs403016 |
| LitVar | rs403016 |
| Map | rs403016 |
| PheGenI | rs403016 |
| Biobank | rs403016 |
| 1000 genomes | rs403016 |
| hgdp | rs403016 |
| ensembl | rs403016 |
| geneview | rs403016 |
| scholar | rs403016 |
| rs403016 | |
| pharmgkb | rs403016 |
| gwascentral | rs403016 |
| openSNP | rs403016 |
| 23andMe | rs403016 |
| SNPshot | rs403016 |
| SNPdbe | rs403016 |
| MSV3d | rs403016 |
| GWAS Ctlg | rs403016 |
| Max Magnitude | 2 |
| ? | (C;C) (C;G) (G;G) | 28 |
|---|---|---|
|
| ||
SNP rs403016 has been reported from a study of 119 Chinese lupus patients to be associated with an increased risk for developing the disease. The odds ratio is 2.2 (p = 0.028). The risk allele is rs403016(G), which encodes the "72R" (R for arginine) allele. [PMID 16716162]
[PMID 17922423] [Study on genetic susceptibility of the single nucleotide polymorphism of FCGR3A gene and systemic lupus erythematosus].
[PMID 18625651] Genetic susceptibility and haplotype analysis between Fcgamma receptor IIB and IIIA gene with systemic lupus erythematosus in Chinese population.
