rs4076128
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 1.8x increased breast cancer risk for women having high linoleic acid diets | |
| (A;G) | normal | |
| (G;G) | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 13 |
| Position | 30731006 |
| Gene | ALOX5AP |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4076128 |
| dbSNP (classic) | rs4076128 |
| ClinGen | rs4076128 |
| ebi | rs4076128 |
| HLI | rs4076128 |
| Exac | rs4076128 |
| Gnomad | rs4076128 |
| Varsome | rs4076128 |
| LitVar | rs4076128 |
| Map | rs4076128 |
| PheGenI | rs4076128 |
| Biobank | rs4076128 |
| 1000 genomes | rs4076128 |
| hgdp | rs4076128 |
| ensembl | rs4076128 |
| geneview | rs4076128 |
| scholar | rs4076128 |
| rs4076128 | |
| pharmgkb | rs4076128 |
| gwascentral | rs4076128 |
| openSNP | rs4076128 |
| 23andMe | rs4076128 |
| SNPshot | rs4076128 |
| SNPdbe | rs4076128 |
| MSV3d | rs4076128 |
| GWAS Ctlg | rs4076128 |
| GMAF | 0.4183 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
Based on a mixed-ethnicity study, women consuming a diet high in linoleic acid (top quartile of intake, >17.4 g/d) and carrying the rs4076128(A;A) genotype were associated with higher breast cancer risk (age- and race-adjusted odds ratio, 1.8, CI: 1.2-2.9) compared with (A;G) and (G;G) genotypes. Among women consuming </=17.4 g/d of linoleic acid, there was no association with breast cancer risk. [PMID 18843019]
[PMID 18366797
] Influence of leukotriene gene polymorphisms on chronic rhinosinusitis.
