rs4147929
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Make rs4147929(A;A) |
| Make rs4147929(A;G) |
| Make rs4147929(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 19 |
| Position | 1063444 |
| Gene | ABCA7 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4147929 |
| dbSNP (classic) | rs4147929 |
| ClinGen | rs4147929 |
| ebi | rs4147929 |
| HLI | rs4147929 |
| Exac | rs4147929 |
| Gnomad | rs4147929 |
| Varsome | rs4147929 |
| LitVar | rs4147929 |
| Map | rs4147929 |
| PheGenI | rs4147929 |
| Biobank | rs4147929 |
| 1000 genomes | rs4147929 |
| hgdp | rs4147929 |
| ensembl | rs4147929 |
| geneview | rs4147929 |
| scholar | rs4147929 |
| rs4147929 | |
| pharmgkb | rs4147929 |
| gwascentral | rs4147929 |
| openSNP | rs4147929 |
| 23andMe | rs4147929 |
| SNPshot | rs4147929 |
| SNPdbe | rs4147929 |
| MSV3d | rs4147929 |
| GWAS Ctlg | rs4147929 |
| Max Magnitude | 0 |
rs4147929 is a SNP in the ATP-binding cassette, sub-family A (ABC1), member 7 ABCA7 gene.
rs4147929 has been reported in a large study (IGAP) to be associated with late onset Alzheimer's disease.
The risk allele (oriented to the dbSNP entry) is (A); the odds ratio associated with heterozygotes is 1.15 (CI 1.11-1.19), [PMID 24443964
]
| GWAS snp | |
|---|---|
| PMID | [PMID 24162737]
|
| Trait | Alzheimer's disease (late onset) |
| Title | Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. |
| Risk Allele | A |
| P-val | 1E-15 |
| Odds Ratio | 1.15 [1.11-1.19] |
[PMID 26141617] Mutations in ABCA7 in a Belgian cohort of Alzheimer's disease patients: a targeted resequencing study
[PMID 29872490] Genome-wide significant risk factors on chromosome 19 and the APOE locus.
