rs4276227
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 1.5x risk | |
| (C;T) | 1.2x risk | |
| (T;T) | 0 | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 3 |
| Position | 32289194 |
| Gene | CMTM8 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4276227 |
| dbSNP (classic) | rs4276227 |
| ClinGen | rs4276227 |
| ebi | rs4276227 |
| HLI | rs4276227 |
| Exac | rs4276227 |
| Gnomad | rs4276227 |
| Varsome | rs4276227 |
| LitVar | rs4276227 |
| Map | rs4276227 |
| PheGenI | rs4276227 |
| Biobank | rs4276227 |
| 1000 genomes | rs4276227 |
| hgdp | rs4276227 |
| ensembl | rs4276227 |
| geneview | rs4276227 |
| scholar | rs4276227 |
| rs4276227 | |
| pharmgkb | rs4276227 |
| gwascentral | rs4276227 |
| openSNP | rs4276227 |
| 23andMe | rs4276227 |
| SNPshot | rs4276227 |
| SNPdbe | rs4276227 |
| MSV3d | rs4276227 |
| GWAS Ctlg | rs4276227 |
| GMAF | 0.3191 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs4276227 has been reported in a large study to be associated with bipolar disorder.
The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with heterozygotes is 1.2 (CI 0.99-1.46), and for homozygotes, 1.49 (CI 1.23-1.81). [PMID 17554300
]
[PMID 19308021] Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort.
