rs4307059
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 2 | Reduced Autism risk |
| (C;T) | 2 | 1.19x risk of Autism |
| (T;T) | 3 | 1.42x risk of Autism |
| Reference | GRCh38 38.1/141 |
| Chromosome | 5 |
| Position | 25967594 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4307059 |
| dbSNP (classic) | rs4307059 |
| ClinGen | rs4307059 |
| ebi | rs4307059 |
| HLI | rs4307059 |
| Exac | rs4307059 |
| Gnomad | rs4307059 |
| Varsome | rs4307059 |
| LitVar | rs4307059 |
| Map | rs4307059 |
| PheGenI | rs4307059 |
| Biobank | rs4307059 |
| 1000 genomes | rs4307059 |
| hgdp | rs4307059 |
| ensembl | rs4307059 |
| geneview | rs4307059 |
| scholar | rs4307059 |
| rs4307059 | |
| pharmgkb | rs4307059 |
| gwascentral | rs4307059 |
| openSNP | rs4307059 |
| 23andMe | rs4307059 |
| SNPshot | rs4307059 |
| SNPdbe | rs4307059 |
| MSV3d | rs4307059 |
| GWAS Ctlg | rs4307059 |
| GMAF | 0.2365 |
| Max Magnitude | 3 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
23andMe blog rs4307059 — compared to two copies of a C, each copy of the more common T version increased the odds of autism by 1.19 times. [1]
[PMID 19404256
] Common genetic variants on 5p14.1 associate with autism spectrum disorders
[PMID 20634369] Association Between a High-Risk Autism Locus on 5p14 and Social Communication Spectrum Phenotypes in the General Population
[PMID 22491950] A noncoding RNA antisense to moesin at 5p14.1 in autism
[PMID 19456320] A genome-wide association study of autism reveals a common novel risk locus at 5p14.1.
[PMID 19812673] A genome-wide linkage and association scan reveals novel loci for autism.
[PMID 22739633] The association of rs4307059 and rs35678 markers with autism spectrum disorders is replicated in Italian families
[PMID 22846907] Analysis of four genes involved in the neurodevelopment shows association of rs4307059 polymorphism in the cadherin 9/10 region with completed suicide.
[PMID 33076578] Genetic Risk of Autism Spectrum Disorder in a Pakistani Population.
