rs4411417
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (T;T) | 0 | common/normal |
| Make rs4411417(C;C) |
| Make rs4411417(C;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 14 |
| Position | 54853845 |
| Gene | GCH1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4411417 |
| dbSNP (classic) | rs4411417 |
| ClinGen | rs4411417 |
| ebi | rs4411417 |
| HLI | rs4411417 |
| Exac | rs4411417 |
| Gnomad | rs4411417 |
| Varsome | rs4411417 |
| LitVar | rs4411417 |
| Map | rs4411417 |
| PheGenI | rs4411417 |
| Biobank | rs4411417 |
| 1000 genomes | rs4411417 |
| hgdp | rs4411417 |
| ensembl | rs4411417 |
| geneview | rs4411417 |
| scholar | rs4411417 |
| rs4411417 | |
| pharmgkb | rs4411417 |
| gwascentral | rs4411417 |
| openSNP | rs4411417 |
| 23andMe | rs4411417 |
| SNPshot | rs4411417 |
| SNPdbe | rs4411417 |
| MSV3d | rs4411417 |
| GWAS Ctlg | rs4411417 |
| GMAF | 0.2658 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence. C allele associated with higher tolerance to pain.[PMID 17057711]
Polymorphisms in the GTP cyclohydrolase gene (GCH1) are associated with ratings of capsaicin pain. C allele associated with higher tolerance to pain.[PMID 19081190
]
[PMID 17343757] Lack of influence of GTP cyclohydrolase gene (GCH1) variations on pain sensitivity in humans.
[PMID 23322459] Association of guanosine triphosphate cyclohydrolase 1 gene polymorphisms with fibromyalgia syndrome in a Korean population.
