rs4537545
| Orientation | plus |
| Stabilized | plus |
| Make rs4537545(C;C) |
| Make rs4537545(C;T) |
| Make rs4537545(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 1 |
| Position | 154446403 |
| Gene | IL6R |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4537545 |
| dbSNP (classic) | rs4537545 |
| ClinGen | rs4537545 |
| ebi | rs4537545 |
| HLI | rs4537545 |
| Exac | rs4537545 |
| Gnomad | rs4537545 |
| Varsome | rs4537545 |
| LitVar | rs4537545 |
| Map | rs4537545 |
| PheGenI | rs4537545 |
| Biobank | rs4537545 |
| 1000 genomes | rs4537545 |
| hgdp | rs4537545 |
| ensembl | rs4537545 |
| geneview | rs4537545 |
| scholar | rs4537545 |
| rs4537545 | |
| pharmgkb | rs4537545 |
| gwascentral | rs4537545 |
| openSNP | rs4537545 |
| 23andMe | rs4537545 |
| SNPshot | rs4537545 |
| SNPdbe | rs4537545 |
| MSV3d | rs4537545 |
| GWAS Ctlg | rs4537545 |
| GMAF | 0.4601 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 19567438
] Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease
[PMID 21552154] Common genetic variation in the IGF1 associates with maximal force output
[PMID 17671508] A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects.
[PMID 18276608] Interleukin-6 (IL-6) and receptor (IL6-R) gene haplotypes associate with amniotic fluid protein concentrations in preterm birth.
[PMID 19197348] Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
[PMID 19249341] Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults.
[PMID 20031577] Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.
[PMID 23372742] Interleukin-6 Receptor Polymorphism Is Prevalent in HIV-negative Castleman Disease and Is Associated with Increased Soluble Interleukin-6 Receptor Levels
[PMID 24971461] Polymorphisms in the Inflammatory Pathway Genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG Are Associated with Susceptibility of Inflammatory Bowel Disease in a Danish Cohort
[PMID 26198920] Family-based association study of interleukin 6 (IL6) and its receptor (IL6R) functional polymorphisms in schizophrenia in the Polish population
[PMID 28769070] IL6R haplotype rs4845625*T/rs4537545*C is a risk factor for simultaneously high CRP, LDL and ApoB levels.
