rs4673993

plus

Geno	Mag	Summary
(T;T)	0	common in clinvar

Make rs4673993(C;C)

Make rs4673993(C;T)

Reference

GRCh38 38.1/141

Chromosome

2

Position

215347616

Gene

ATIC

is a	snp
is	mentioned by
dbSNP	rs4673993
dbSNP (classic)	rs4673993
ClinGen	rs4673993
ebi	rs4673993
HLI	rs4673993
Exac	rs4673993
Gnomad	rs4673993
Varsome	rs4673993
LitVar	rs4673993
Map	rs4673993
PheGenI	rs4673993
Biobank	rs4673993
1000 genomes	rs4673993
hgdp	rs4673993
ensembl	rs4673993
geneview	rs4673993
scholar	rs4673993
google	rs4673993
pharmgkb	rs4673993
gwascentral	rs4673993
openSNP	rs4673993
23andMe	rs4673993
SNPshot	rs4673993
SNPdbe	rs4673993
MSV3d	rs4673993
GWAS Ctlg	rs4673993

GMAF

0.23

Max Magnitude

0

?

(C;C) (C;T) (T;T)

28

[PMID 20847201] Using genetic and clinical data to understand response to disease-modifying anti-rheumatic drug therapy: data from the Brigham and Women's Hospital Rheumatoid Arthritis Sequential Study

[PMID 19193698 ] Investigation of candidate polymorphisms and disease activity in rheumatoid arthritis patients on methotrexate.

ClinVar
Risk	rs4673993(C;C)
Alt	rs4673993(C;C)
Reference	Rs4673993(T;T)
Significance	Drug-response
Disease	methotrexate response - Efficacy
Variation	info
Gene	ATIC
CLNDBN	methotrexate response - Efficacy
Reversed	0
HGVS	NC_000002.11:g.216212339T>C
CLNSRC	PharmGKB Clinical Annotation
CLNACC	RCV000211326.1,