rs4713916
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common in clinvar |
| Make rs4713916(A;G) |
| Make rs4713916(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 35702206 |
| Gene | FKBP5 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4713916 |
| dbSNP (classic) | rs4713916 |
| ClinGen | rs4713916 |
| ebi | rs4713916 |
| HLI | rs4713916 |
| Exac | rs4713916 |
| Gnomad | rs4713916 |
| Varsome | rs4713916 |
| LitVar | rs4713916 |
| Map | rs4713916 |
| PheGenI | rs4713916 |
| Biobank | rs4713916 |
| 1000 genomes | rs4713916 |
| hgdp | rs4713916 |
| ensembl | rs4713916 |
| geneview | rs4713916 |
| scholar | rs4713916 |
| rs4713916 | |
| pharmgkb | rs4713916 |
| gwascentral | rs4713916 |
| openSNP | rs4713916 |
| 23andMe | rs4713916 |
| SNPshot | rs4713916 |
| SNPdbe | rs4713916 |
| MSV3d | rs4713916 |
| GWAS Ctlg | rs4713916 |
| GMAF | 0.219 |
| Max Magnitude | 0 |
[PMID 20709156] Meta-analysis of FKBP5 gene polymorphisms association with treatment response in patients with mood disorders
[PMID 15637659
] Linkage disequilibrium patterns and tagSNP transferability among European populations.
[PMID 17081296] Is FKBP5 a genetic marker of affective psychosis? A case control study and analysis of disease related traits.
[PMID 18191112] The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort.
[PMID 18349090] Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults.
[PMID 18702710] Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls.
[PMID 19676097] FKBP5 polymorphisms and antidepressant response in geriatric depression.
[PMID 21172166] Pharmacogenetics of antidepressant response.
[PMID 21788965] Glucocorticoid resistance in Crohn's disease and ulcerative colitis: an association study investigating GR and FKBP5 gene polymorphisms.
[PMID 23429203] FKBP5 as a possible moderator of the psychosis-inducing effects of childhood trauma.
[PMID 24856550] FKBP5 polymorphism is associated with major depression but not with bipolar disorder
| ClinVar | |
|---|---|
| Risk | rs4713916(G;G) |
| Alt | rs4713916(G;G) |
| Reference | Rs4713916(A;A) |
| Significance | Drug-response |
| Disease | fluoxetine response - Efficacy Selective serotonin reuptake inhibitors response - Efficacy mirtazapine response - Efficacy antidepressants response - Efficacy venlafaxine response - Efficacy paroxetine response - Efficacy citalopram response - Efficacy |
| Variation | info |
| Gene | FKBP5 |
| CLNDBN | fluoxetine response - Efficacy Selective serotonin reuptake inhibitors response - Efficacy mirtazapine response - Efficacy antidepressants response - Efficacy venlafaxine response - Efficacy paroxetine response - Efficacy citalopram response - Efficacy |
| Reversed | 0 |
| HGVS | NC_000006.11:g.35669983A>G |
| CLNSRC | PharmGKB Clinical Annotation |
| CLNACC | RCV000211171.1, RCV000211195.1, RCV000211257.1, RCV000211263.1, RCV000211285.1, RCV000211378.1, RCV000211385.1, |
[PMID 28889074] Interaction between FKBP5 gene and childhood trauma on psychosis, depression and anxiety symptoms in a non-clinical sample.
