rs4870044
| Orientation | plus |
| Stabilized | plus |
| Make rs4870044(C;C) |
| Make rs4870044(C;T) |
| Make rs4870044(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 151580274 |
| Gene | CCDC170 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4870044 |
| dbSNP (classic) | rs4870044 |
| ClinGen | rs4870044 |
| ebi | rs4870044 |
| HLI | rs4870044 |
| Exac | rs4870044 |
| Gnomad | rs4870044 |
| Varsome | rs4870044 |
| LitVar | rs4870044 |
| Map | rs4870044 |
| PheGenI | rs4870044 |
| Biobank | rs4870044 |
| 1000 genomes | rs4870044 |
| hgdp | rs4870044 |
| ensembl | rs4870044 |
| geneview | rs4870044 |
| scholar | rs4870044 |
| rs4870044 | |
| pharmgkb | rs4870044 |
| gwascentral | rs4870044 |
| openSNP | rs4870044 |
| 23andMe | rs4870044 |
| SNPshot | rs4870044 |
| SNPdbe | rs4870044 |
| MSV3d | rs4870044 |
| GWAS Ctlg | rs4870044 |
| GMAF | 0.4564 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs4870044 increases susceptibility to Bone mineral density variations, lower for carriers of the T allele [PMID 18445777]
| GWAS | |
|---|---|
| SNP | rs4870044 |
| PubMedID | [PMID 18445777] |
| Condition | Bone mineral density (spine) |
| Gene | ESR1 |
| Risk Allele | T |
| pValue | 2.00E-011 |
| OR | 0.11 |
| 95% CI | 0.08-0.14) SD decreas |
[PMID 22022476
] Common genetic variants are associated with accelerated bone mineral density loss after hematopoietic cell transplantation
[PMID 21646926] Interactions of osteoporosis candidate genes for age at menarche, age at natural menopause, and maximal height in Han Chinese women
[PMID 19181680] Common variants in the region around Osterix are associated with bone mineral density and growth in childhood.
[PMID 19629617] Replication study of candidate genes/loci associated with osteoporosis based on genome-wide screening.
[PMID 20072603] Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis.
[PMID 24481879] Association of ESR1 and C6orf97 gene polymorphism with osteoporosis in postmenopausal women
[PMID 23074152] Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women.
[PMID 28253304] Bone mineral density is associated with vitamin D related rs6013897 and estrogen receptor polymorphism rs4870044: The Tromsø study.
