rs4938369
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 1.6x increased risk for Alzheimer's | |
| (C;T) | ? | |
| (T;T) | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 11 |
| Position | 117317404 |
| Gene | BACE1, CEP164 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4938369 |
| dbSNP (classic) | rs4938369 |
| ClinGen | rs4938369 |
| ebi | rs4938369 |
| HLI | rs4938369 |
| Exac | rs4938369 |
| Gnomad | rs4938369 |
| Varsome | rs4938369 |
| LitVar | rs4938369 |
| Map | rs4938369 |
| PheGenI | rs4938369 |
| Biobank | rs4938369 |
| 1000 genomes | rs4938369 |
| hgdp | rs4938369 |
| ensembl | rs4938369 |
| geneview | rs4938369 |
| scholar | rs4938369 |
| rs4938369 | |
| pharmgkb | rs4938369 |
| gwascentral | rs4938369 |
| openSNP | rs4938369 |
| 23andMe | rs4938369 |
| SNPshot | rs4938369 |
| SNPdbe | rs4938369 |
| MSV3d | rs4938369 |
| GWAS Ctlg | rs4938369 |
| GMAF | 0.1125 |
| Max Magnitude | 0 |
rs4938369, also known as -918G/A, is a SNP in the beta-site APP-cleaving enzyme 1 BACE1 gene.
A case-control study (429 cases and 346 controls of Han Chinese descent) reported that rs4938369(C;C) homozygotes had a 1.67x higher risk for sporadic Alzheimer's disease than (C;T) or (T;T) individuals (odds ratio 1.667, CI: 1.087-2.556, p = 0.019).[PMID 19441127]
